Evaluation of Anti-anxiety Activity of Grangeamaderaspatana(L.)Poir. Extracts in Experimental Animals

Abstract

Grangeamaderaspatana (L.)Poiris a popular Indian medicinal plant belonging to Asteraceae family. This plant is commonly known as Madras Carpetandisgrown in wet places. It has long been used in traditional Ayurvedic Indian medicine for various diseases. A wide range of phytochemical constituents have been isolated from this plant. This plant is pharmacologically studied for oestrogenicity, antifertility, analgesic, anti-inflammatory, antiarthritic, cytotoxic, antioxidant, hepatoprotective, diuretic and antimicrobial activities.Despite the widespread uses of the plant, no scientific work is reported in the literature regarding the effect of G. maderaspatana against anxiety like states. Chloroform (200 mg/kg, 400 mg/kg) and methanol extracts (200 mg/kg, 400 mg/kg) of G. maderaspatanawere evaluated for anti-anxiety activity in mice using elevated plus maze apparatus. Among all these extracts, chloroform extract exhibited significant anti-anxiety activity at a dose of 400 mg/kg in mice with respect to control.The chloroform and methanol extract of Grangeamaderaspatana possess significant anti-anxiety activity due presence of terpenoids, steroids and saponin.

Authors and Affiliations

Tanvi Dodiya, Vineet Jain

Keywords

Related Articles

To Study the Efficacy of Amaltas Kwath in Ek Kushtha

Ekkushta is a type of Kshudrakushtha described in Ayurveda . It is a Vata-kaphaj disorder. The clinical symptoms of Ekkushta described in Ayurveda resembles with the clinical symptoms of Psoriasis. The clinical features...

A Conceptual Study of Dry Eye Symptom Complex as a Purvaroopa of Netraroga in Over Users of Computer

In today’s lifestyle a man can have all sorts of facilities available at finger touch. Though due to this, life of man is becoming luxurious but it has some ill effects on health. Extreme interference of electronic instr...

Effect of Takravasti in Grahaniroga–A Case Study

Introduction: Ayurveda is the ancient system of medicine having special impact in the management of disorders where involvement of digestive fire such as grahaniroga, atisara, pravahika etc.Takra is like nectar in the ma...

Global Market Analysis of Herbal Drug Formulations

As per the WHO reports, about three-quarters of the world’s population currently use herbs and other forms of traditional medicines to treat disease. Even though marvelous advancement occurred in Allopathic system of med...

Pharmaceutical Study of Vanga Bhasma

Vanga bahasma is a type of herbo-mineral preparation. Usage of herbo minerals as therapeutic agents has been in practice since centuries. Ayurvedic system of medicine should be considered the pioneer regarding the pharma...

Download PDF file
  • EP ID EP285761
  • DOI -
  • Views 56
  • Downloads 0

How To Cite

Tanvi Dodiya, Vineet Jain (2017). Evaluation of Anti-anxiety Activity of Grangeamaderaspatana(L.)Poir. Extracts in Experimental Animals. International Journal of Ayurveda and Pharmaceutical Chemistry, 0(0), 1-8. https://europub.co.uk/articles/-A-285761