Evaluation of Antibacterial Activity of Flowers of Moringa Oleifera Lam
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2018, Vol 0, Issue 0
Abstract
Background: Moringa Oleifera Lam.(Shigru) is a well-known drug in Ayurveda used for its Krimighna activity (ability to kill the pathogens). Acharya Charaka had mentioned Shigru in Krimighna1 Mahakashaya. Whereas, some nighantus had specifically mentioned Krimighna activity of flowers of Moringa Oleifera Lam.viz. Kaiyadeva2 Nighantu and Shaligram3 Nighantu. Therefore,powder of flowers (Shigru Pushpa Churna) is selected for evaluation of anti-bacterial activity on the strains which affects a large number of population. Methods: Shigru Pushpa churna was tested for anti-bacterial activity at different concentrations viz., 5µl, 10µl, 25µl, 50µl and 75µl, by Disc Diffusion method for 2 strains of Gram positive and 2 strains of Gram negative bacteria each, with DMSO (Dimethyl Sulphoxide) a neutral solvent. Result: Shigru Pushpa inhibits growth of Staphylococcus aureus, Streptococcus mutans, Pseudomonas auringinosa and Escheria coli at higher concentrations of 50µl and 75µl whereas it is resistant at 5µl, 10µl and 25µl . Zone of inhibition was 13mm for Staphylococcus aureus, 13mm for Streptococcus mutans, 12mm for Pseudomonas auringinosa, 20mm for Escheria coli and activity index were 0.86, 0.43, 0.48 and 0.50, respectively. Conclusion: Shigru Pushpa possess good anti bacterial activity against Staphylococcus aureus, Streptococcus mutans, Pseudomonas auringinosa and Escheria coli.
Authors and Affiliations
Abhijeet D. Kumbhar, Vamsikrishna G. K, Surekha Khot
Keywords
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