Evaluation of Antibacterial Activity of Thiazolo-Thiourea Sydnones
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 4
Abstract
Abstract: Sydnones are the mesoionic compounds having wide range of biological activities. Structural modifications at various positions have provided different class of sydnones, thiazolo-thiourea sydnones are one among them. Nowadays Greenfield chemistry revolves around the design and development of chemical compounds in feasible economical and nonhazardous way. Ten different thiazolo thiourea sydnones compounds were tested for their antibacterial activity. They were tested on Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas pyocyneous using agar well method. Out of the ten different Thiazolo thiourea sydnones derivatives compounds 2, 3 and 10 showed promising results others also had some antibacterial activity. It can be concluded from the above study that Thiazolo thiourea compounds have antibacterial property. Keywords: Antibacterial property, Thiazolo-thiourea sydnones, Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Pseudomonas pyocyneous
Authors and Affiliations
Jagadeesh K, Shreenivas Revankar
Keywords
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