Evaluation of Antibiotics Use and Bacteria Profile of Caesarean Section at Regional General Hospital, Pasuruan
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2018, Vol 7, Issue 2
Abstract
Surgical Site Infection (SSI) is one of the most common surgical complications in the world, especially in developing countries. Proper use of prophylaxis antibiotics in appropriate intraoperative procedures may reduce SSI. The aim of this study was to determine the profile of antibiotic used and the adherence of antibiotic in caesarean section to Hospital Guideline 2016, Hospital Formulary, National Formulary, bacteria profile that cause SSI on the patient’s wound. Method used in this study was cohort prospective study design using record data of patients who underwent caesarean section surgery at Regional General Hospital of Pasuruan from March–May 2017, i.e. antibiotics usage data (type, dosage and time of delivery) and microbial pattern data about antibiotic resistance from January–March 2017. Data analysis was description of the profile of antibiotic use, adherence use of antibiotic of caesarean section inpatients to the guidelines, and profile of bacteria that cause SSI. The results showed that the use of antibiotics in caesarean section patients was ampicillin/sulbactam 37%, cefuroxime 34%, ceftriaxone 24%, cefazolin 5%, metronidazole 1%, and gentamycin 1%. Adherence by type of antibiotics was 5% based on Hospital Guideline, 100% based on Hospital Formulary and 63% based on National Formulary. This was due to a decrease of cefazolin sensitivity pattern from 20% to 0% in January–March 2017 period. Adherence of antibiotic dosage was 100% based on Hospital Guideline, Hospital Formulary and National Formulary. Adherence of time of delivery 92% was based on Hospital Guideline. Bacteria found in the wounds of patients was Hafnia alvei.
Authors and Affiliations
Rika Yulia, Fauna Herawati, Abdul K. Jaelani, Wirda Anggraini
Keywords
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- EP ID EP370260
- DOI 10.15416/ijcp.2018.7.2.69
- Views 94
- Downloads 0
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