EVALUATION OF ANTIMICROBIAL ACTIVITY AND PRELIMINARY PHYTO-CHEMICAL STUDIES ON WHOLE PLANT OF STACHYTARPHETA JAMAICENSIS (L.)VAHL
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 3
Abstract
The antimicrobial activity and preliminary phyto-chemical studies on whole plant of Stachytarpheta jamaicensis were evaluated. The shade dried and coarsely powdered plant was successively extracted with n-hexane, chloroform and alcohol in Soxhlet apparatus. The antimicrobial activity of chloroform and alcohol extracts were evaluated by disc diffusion method and the MIC was determined. Preliminary phyto-chemical studies were carried out in n-hexane, chloroform and alcohol extracts. The studies revealed that more antimicrobial activity was observed with chloroform extract against the gram positive organisms like Staphylococcus aureus, Enterococcus faecalis and Bacillus subtilis when compared with alcohol extract. The chloroform and alcohol extract exhibited antifungal activity against Candida albicans and Saccharomyces cerevisiae. The preliminary phyto-chemical studies of all the extracts revealed that the plant has many phyto-constituents. The potent antimicrobial activity and the presence of phytoconstitutents as known by the studies helps in concluding that the plant S. jamaicensis can be used as a novel source for drug development.
Authors and Affiliations
Meena Rampratap , Pitchai R
Keywords
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