EVALUATION OF BACTERICIDAL ACTIVITY OF AN ANTISEPTIC GELTHROUGH THE DILUTION-NEUTRALIZATION METHOD

Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 2

Abstract

Objective: To evaluate the bactericidal activity of an antiseptic gel for hygiene and disinfection of the hands by rubbing. Methods: The dilution-neutralization method was used according to Colombian Technical Standard NTC, 2009, 12, 16 in Instituto Colombiano de Normas Técnicas y Certificación (ICONTEC), 5 strains, over 6 different types and with 6 replicas per time were exposed to the antiseptic gel, using Letheen Broth as a neutralizer substance. Results: A 99% of reduction was obtained with Staphylococcus aureus 6538, Enterococos hirae 10541, Pseudomonas aeruginosa 15442 and Klebsiella sp, within the first 30 s of exposure to the gel and within the first 60 s of exposure using the Escherichia coli 19538. All strains used coming from American Type Culture Collection (ATCC). Conclusion: It was confirmed that the product is effective. In presence of a neutralizer substance, the microorganisms were not inhibit, so the growing reduction occurs due to the action of the product.

Authors and Affiliations

Janeth Del Carmen Arias-Palacios, LIBARDO HERNANDEZ ESQUIVEL, Dorelly Sandoval Medina, Tatiana Diaz B.

Keywords

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  • EP ID EP566029
  • DOI 10.22159/ijpps.2019v11i2.25716
  • Views 73
  • Downloads 0

How To Cite

Janeth Del Carmen Arias-Palacios, LIBARDO HERNANDEZ ESQUIVEL, Dorelly Sandoval Medina, Tatiana Diaz B. (2019). EVALUATION OF BACTERICIDAL ACTIVITY OF AN ANTISEPTIC GELTHROUGH THE DILUTION-NEUTRALIZATION METHOD. International Journal of Pharmacy and Pharmaceutical Sciences, 11(2), 17-20. https://europub.co.uk/articles/-A-566029