EVALUATION OF BACTERICIDAL ACTIVITY OF AN ANTISEPTIC GELTHROUGH THE DILUTION-NEUTRALIZATION METHOD
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 2
Abstract
Objective: To evaluate the bactericidal activity of an antiseptic gel for hygiene and disinfection of the hands by rubbing. Methods: The dilution-neutralization method was used according to Colombian Technical Standard NTC, 2009, 12, 16 in Instituto Colombiano de Normas Técnicas y Certificación (ICONTEC), 5 strains, over 6 different types and with 6 replicas per time were exposed to the antiseptic gel, using Letheen Broth as a neutralizer substance. Results: A 99% of reduction was obtained with Staphylococcus aureus 6538, Enterococos hirae 10541, Pseudomonas aeruginosa 15442 and Klebsiella sp, within the first 30 s of exposure to the gel and within the first 60 s of exposure using the Escherichia coli 19538. All strains used coming from American Type Culture Collection (ATCC). Conclusion: It was confirmed that the product is effective. In presence of a neutralizer substance, the microorganisms were not inhibit, so the growing reduction occurs due to the action of the product.
Authors and Affiliations
Janeth Del Carmen Arias-Palacios, LIBARDO HERNANDEZ ESQUIVEL, Dorelly Sandoval Medina, Tatiana Diaz B.
Keywords
Related Articles
- EP ID EP566029
- DOI 10.22159/ijpps.2019v11i2.25716
- Views 65
- Downloads 0
ANTIDIABETIC EFFECT OF THYMUS SATUREIOIDES AQUEOUS EXTRACT IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
Objective: The aerial parts of Thymus satureioides have been traditionally used to treat diabetes mellitus and its complications in Morocco. The aim of the present study was to investigate the antidiabetic and antihyperl...
SIMULTANEOUS DETERMINATION OF TARTRAZINE AND BRILLIANT BLUE IN FOODSTUFFS BY SPECTROPHOTOMETRIC METHOD
Objective: Objective of the study was to develop a simple spectrophotometric method for simultaneous determination of two colorants, Tartrazine (T) and Brilliant Blue (BB), in foodstuffs without any prior treatment.Metho...
EMBEDMENT TECHNIQUE: AN ALTERNATIVE TO WET GRANULATION FOR BETTER CONTROL OF RELEASE OF HIGHLY WATER SOLUBLE DRUGS–A CASE STUDY WITH DILTIAZEM HCl
Objective: Extending or controlling the release of highly water soluble drugs from matrix tablets is always a challenge. The research attempt was aimed to explore the embedment technique for the development of extended r...
SEPARATION AND DETERMINATION OF THE S-ISOMER OF (10-CAMPHORSULFONYL) OXAZIRIDINE IN A BULK DRUG SUBSTANCE BY NORMAL-PHASE LIQUID CHROMATOGRAPHY
Objective: To develop novel, simple and accurate enantiomeric separation of (10-Camphorsulfonyl) oxaziridine by normal-phase high-performance liquid chromatographic method as per ICH guidelines.Methods: The S-isomer and...
DRUG UTILISATION REVIEW IN POSTOPERATIVEPATIENTS IN OBSTETRICS-GYNAECOLOGY AND SURGICAL GASTROENTEROLOGY DEPARTMENTS-A RETROSPECTVE STUDY
Objective: The main objectives of our study include classification, analysis and assessment of all the post-operative drugs present of our study.Methods: The current project being a retrospective drug utilization review...