EVALUATION OF BIOCHEMICAL (TROPONIN-I) AND ECHOCARDIOGRAPHIC OUTCOMES OF REMOTE ISCHAEMIC PRECONDITIONING IN PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 25
Abstract
BACKGROUND Percutaneous coronary interventions are associated with myocyte damage. The repetitive brief periods of ischaemia protect the myocardium from a subsequent longer ischaemic insult and has been reported to reduce infarct size, preserve vascular endothelial function, decrease neutrophil accumulation and reduce apoptosis. However, this hypothesis remains debatable. The studies done so far have yielded heterogeneous results.1 MATERIALS AND METHODS This was a randomised controlled study. This study compared effect of remote ischaemic preconditioning on changes in cardiac biomarker and echocardiographic parameters in patients undergoing elective coronary intervention. RESULTS The study outcomes were comparable in the two groups with remote ischaemic preconditioning with no statistically significant differences. CONCLUSION The study concludes an insignificant impact of remote ischaemic preconditioning on these outcome parameters
Authors and Affiliations
Smit Shrivastava, Sanjay Varma, Archana Toppo, Saurabh Jagtap
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