Evaluation of Blood Banked Fibrin Glue versus Blood Banked Platelet Glue as a Local Hemosatic Agent and a Healing Promoter in Patients with Acute Leukemia Undergoing Tooth Extraction
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 21, Issue 7
Abstract
Aims: The purpose of this study was to compare the effectiveness of blood banked platelet glue and blood banked fibrin glue as a local hemostatic agent after tooth extraction in patients diagnosed with acute leukemia with concomitant thrombocytopenia. Study Design: Randomized clinical trial. Place and Duration of Study: Hematology Unit, Internal Medicine Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt between June 2015 and July 2016. Methodology: 21 patients who underwent 60 dental extractions diagnosed with acute leukemia with concomitant thrombocytopenia; age between 25-45 years were included in this study. Patients were randomly allocated into three groups: Group I (control group) patients had underwent platelet transfusion before tooth extraction and was continued after the extraction if re-bleeding occurred, Group II (Fibrin Group) Fibrin glue used as a local hemostatic agent after tooth extraction; and Group III (Platelet group) platelet glue used as a local hemostatic agent after tooth extraction. Immediate and delayed evaluation by monitoring time to hemostasis (secs), postoperative complications; fever, localized gingival inflammation, disintegrated blood clot, wound dehiscence, wound infection and time in days for healing. Statistical software SPSS v.17.0 was used for statistical analysis. Results: Time to hemostasis (secs) was 12.57 ± 1.51 sec, 9.57 ± 2.57 sec, and 9.43 ± 2.44 sec for group I, II and III respectively, significant difference at P- value (P≤0.05) was found between three groups. Wound healing time was 16.00 ± 3.51 days, 10.00 ± 1.00 days and 7.29 ± 0.95 days in Group I, Group II and Group III respectively, significant difference at P- value (P≤0.05) was found between three groups. Conclusion: Blood banked platelet glue has excellent hemostatic action and can be used successfully as a local hemostasis after tooth extraction.
Authors and Affiliations
Suzan Salem, Islam Saad
Role of Different Ovulation Induction Protocols in Follicular Growth, Estradiol and Pregnancy Rates for Women with Unexplained Infertility and Polycystic Ovary Syndrome Undergoing Intrauterine Insemination
Introduction: The study aimed to study the effects of ovulation induction programs on the number of pre-ovulatory dominant follicles and endometrial thickness, their effects on pre-ovulatory estradiol 2 levels, and to de...
Surgical-outcome and Complication Differences between Frontal and Posterior Parietal Ventriculo-peritoneal Shunts in Iraqi
Background: Hydrocephalus, an abnormal expansion of cerebral ventricles caused by the accumulation of cerebrospinal fluid (CSF), is estimated to occur in about 3 of 1,000 live births. With a peak age of less than 10 year...
Globotriaosylceramide (GL-3) Accumulation in the Renal Biopsy of a 1-year-old Patient with Fabry Disease and Ureteropelvic Junction Obstruction
Introduction: Fabry disease is a x-chromosome hereditary disease with an incidence of 1/40000 newborns. Nowadays it presents as much in males as in females and its first clinical symptoms are seen in pediatric patients....
Neuro-epidemiology of Acute Stroke Syndrome in the Adult Emergency Department of a Tertiary Hospital in a Resource-limited Environment of South-eastern Nigeria
Background: Globally, acute stroke is one of the leading causes of preventable emergency hospital admissions. It is emerging as an important cause of disability and mortality among adult Nigerian Africans in the emergenc...
Dietary Risk Factors for Sporadic Creutzfeldt-Jakob Disease: A Confirmatory Case-Control Study
Aims: This study’s primary purpose was to determine whether earlier findings suggesting an association between sporadic Creutzfeldt-Jakob disease (sCJD), a transmissible spongiform encephalopathy of humans and specific d...