Evaluation of C-Reactive Protein and Procalcitonin in Sepsis
Journal Title: IJSR-International Journal Of Scientific Research - Year 2016, Vol 5, Issue 7
Abstract
Early diagnosis and appropriate therapy of sepsis is a daily challenge in the emergency room and in intensive care unit. In addition non infectious clinical syndromes can exhibit sepsis like symptoms, thereby making a diagnosis of sepsis more difficult . Today various therapeutic strategies are known to improve survival in patients with sepsis, therefore rapid and accurate diagnosis is essential . In sepsis there is lack of specific clinical symptoms and signs. Microbiological cultures require time , do not reflect the host response of systemic inflammation and may not be positive in sepsis patients. For a number of reasons even if cultures are positive , it is not enough evidence to discriminate infection and colonization. Procalcitonin and CRP are valuable markers for the diagnosis and prognosis of sepsis. Sequential quantitative estimation and comparison of CRP and Procalcitonin in serum by ELISA method in 30 patients suspected to be suffering from septicaemia with out any history of parenteral antibiotics were included in the study. Serum Procalcitonin and CRP levels were estimated sequentially i.e. on day of admission , after 48 hours and on fourth day , as sequential measurement have greater diagnostic impact than single measurement. The overall corelation between Procalcitonin and CRP is 83.3%. Thus both serological markers are complimentary to each other. Sequential testing of procalcitonin and CRP are helpful in diagnosis and prognosis of sepsis.
Authors and Affiliations
Venkateswarlu . M, T. Dinesh Kumar Singh, K. Saileela, P. LVasantha
Keywords
Related Articles
- EP ID EP336107
- DOI -
- Views 45
- Downloads 0
A STUDY ON FACTORS AFFECTING CUSTOMER'S CHOICE OF SHOPPING MALLS
Shopping malls draw the attention of both sellers and buyers and provide sufficient time to customers for making choices and recreational options in shopping. Meanwhile, stiff competition between malls and usual shopping...
EFFECTIVE DEBRIDEMENT AND SUBSEQUENT OBTURATION OF TOOTH WITH MORPHOANATOMIC VARIATIONS IN NON SYNDROMIC PATIENTS– A SERIES OF 3 CASE REPORTS
Taurodontism is a morphoanatomical anomaly of teeth characterised by enlarged pulp chamber with apically displaced pulp chamber floor and furcation.Endodontic treatment of a taurodont is challenging and requires special...
A STUDY OF MECHANICAL OCULAR INJURIES IN A TERTIARY CARE HOSPITAL IN NORTH BENGAL
Background: Ocular injury is an important public health hazard. It is an important cause of visual loss and disability. Many ocular injuries are avoidable causes of blindness and visual impairment.[1] Ocular injury is a...
THE INFANT FEEDING PRACTICES AMONG THE LACTATING MOTHERS OF MANSA DEVI AREA LOCATED IN PANCHKULA, HARYANA.
Background: Malnutrition has been responsible for 60% of the 10.9 million deaths annually among children under five. 2/3 of these deaths are associated with inappropriate infant feeding practices. The nutritional status...
Osteoarticular tuberculosis of Elbow: A Rare Case Report
Mycobacterial infections of the upper extremities are rare with musculoskeletal system involvement in 1-3% of tuberculosis patients and accounts for 10% of all extra-pulmonary tuberculosis. Elbow joint is most frequently...