Evaluation of CA125 and CA19-9 during different Stages of Urothelial Carcinoma In Pre and Post-therapeutic level
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
The aim of the study was to evaluate the role of CA125 and CA19-9 tumour markers in different stages of urothelial carcinoma and monitoring the response to therapy. Several levels of CA125 and CA19-9 (each purchased from Fujirebio Diagnostics, Sweden) was measured by ELISA before and 7 days after treatment of different stages of 182 urothelial carcinoma patients and compared with the 200 normal subjects as control. The results showed that among 182 urothelial cases, the median serum level of CA125 and CA19-9 were 107.7U/ml, 118.6U/ml, 120.4U/ml and 73.1U/ml, 81.1U/ml, 196.4U/ml in case of superficial transitional cell carcinoma, muscle invasion and metastatic variety respectively. The fall of the titre of CA125 were 90.6%, 91.4%, 81.7% and CA19.9 were 87.1%, 85.8%, 85.1% in case of transitional cell carcinoma, muscle invasion and metastatic variety respectively. The study revealed that CA125 and CA19-9 could be prognostic markers of urothelial carcinoma.
Authors and Affiliations
Dr. Mallika Biswas, Dr. Tarun Biswas, Dr. Juthika Biswas
Keywords
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- EP ID EP374921
- DOI 10.9790/0853-1705096672.
- Views 84
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