Evaluation of Cardiac Function & Dyssynchrony in Patients Undergoing Cardiac Resynchronization Therapy Using Speckle Tracking Technique
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Since approval of Food & drug administration (FDA) on Cardiac resynchronization therapy (CRT) in 2001, CRT become one of the mainstay in treatment of patients with heart failure and left bundle branch Block (LBBB). Hence ; specific echocardiographic parameters is mandatory to identify patients who did respond and those who didn’t respond to CRT and to extent of linking baseline Dyssynchrony parameters & risk factors history of Ischemic Heart Disease & diabetes with their response. The aim of this study is to identify the role of Longitudinal strain & Dyssynchrony parameters in three months follow up of patients with CRT. Study Population: eighteen patients with symptomatic Heart Failure with symptomatic Heart failure & New York Heart Association functional classification (NYHA) class II or IV symptoms, all patients included in this Study were with Sinus rhythm, prolonged QRS >120 milliseconds & their Left ventricular EF < 35%. All patients treated with CRT in Cardiology Unit, Baghdad Teaching Hospital, Medical City, Baghdad-Iraq. Method: in this Before & After study, different methods for Evaluation of ventricular synchrony were used, Both Convectional Echocardiography for Dyssynchrony parameters, ejection fraction (%) & Longitudinal Stain Imaging using Speckle tracking were made to all patients at Baseline and three months after implantation of CRT. Results: at three months, all patients show significant improvement in EF% from 26.02(2.8) to 36.94(8.32) (p0.014), SPWMD from (206.27±47.30) to (37.89±7.56) (p0.023), IVMD from (48.33±17.04) to (25.77±7.00) (p 0.002), while GLS show non-significant change (p0.16). Conclusion, conventional synchrony parameter not enough to predict cardiac future remodeling, Longitudinal Strain is useful tool to identify early cardiac remodeling before being clinically significant.
Authors and Affiliations
Affan Ezzat Hasan, Fahad Abbas Abdul Rahman, Ghazi Farhan Haji, Ghassan Mohammed Mahmoud
Keywords
Related Articles
- EP ID EP243718
- DOI 10.9790/0853-1610067074
- Views 72
- Downloads 0
Langerhans Cell Histiocytosis: Rare Disease Treated With Chemotherapy and Radiotherapy
Langerhans Cell Histiocytosisrepresents a rare benign disorder previously designated as Histiocytosis X Varity” Type II Histiocytosis or Langerhans cell Granulomatosis, it occurs when the body accumulates too many immatu...
A Clinical Study of Displacement of Lens
A total of 52 cases of displacement of lens are studied from out patients Sarojini Devi Eye Hospital, Hyderabad with special reference to the cause of dislocation, associated ocular complications and management. The stud...
Jodhpur disease (Primary acquired gastric outlet obstruction in infancy and childhood): A rare case
Jodhpur disease (Primary acquired gastric outlet obstruction in infancy and childhood) is a rare clinical entity causing symptoms of gastric outlet obstruction. This disease was first described in 1997 in Jodhpur, India....
Compliance to Head and Neck Radiotherapy in Our Patient Population
Background: The treatment of head and neck cancer is complex, costly, toxic and challenging particularly in this part of the world where majority of the patients are from rural background and lower socioeconomic status....
Evolution of Denture Base Materials from Past to New Era
Computer-aided technology is an emerging method for fabricating complete dentures. Consolidated information about historical background, current status, and scope for the future is lacking. The purpose of this literature...