EVALUATION OF COAGULATION PROFILE IN PATIENTS WITH PREGNANCY INDUCED HYPERTENSION IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL IN NORTH INDIA.

Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 6

Abstract

Pregnancy induced hypertension (PIH) is one of the most common causes of both maternal and neonatal morbidity and associated with adverse pregnancy outcomes.Profound changes in coagulation and fibrinolytic system occur during normal pregnancy causing hypercoagulable state. Early identification of high risk women and monitoring derangements in their coagulation system are surely pivotal in the prevention of complications. Hence, this study was undertaken to compare the coagulation profile in pre-eclamptic and eclamptic patients with normotensive pregnant patients Hypertension is one of the common medical complications of pregnancy and contributes significantly to maternal and perinatal morbidity and mortality. Hypertension is a sign of an underlying pathology which may be pre-existing or appear for the first time during pregnancy. Various haematological changes like numerical and functional platelet abnormalities, alteration in haemoglobin and erythrocyte parameters and hypercoagulable state may be seen. Aims and Objectives: Evaluation of coagulation profile in PIH. Materials and Methods: A one year study was carried in the department of gynaecology and obstetrics on 100 PIH cases. Coagulation profile (PT, aPTT, INR and D-dimer) was done in all cases and values were correlated with the severity of PIH. Results: Total of 100 cases were included in the study. 32 were mild GH, 17cases were severe GH, 35 cases were mild pre-eclampsia and 16cases were in severe pre-eclampsia group. Prolonged PT, aPTT and D-Dimer was seen in 15 cases, 42 cases and 38 cases respectively. In our study we observed increased mean aPTT of 31.61+-2.89 and increased D-Dimer of 0.34?0.31 in severe pre-eclampsia patients. Hence we emphasize that raised aPTT, D-Dimer are alarming signs for aggressive treatment. Conclusion: Raised aPTT and D-dimer are fairly good indicator of severe pre-eclampsia and needs aggressive treatment.

Authors and Affiliations

Farhat Ali Lone, Sabha Malik, Shaheera Ajaz, Liaqat Ahmad Malik, Parvaiz Mohiudin Dar.

Keywords

Related Articles

DESIGN OF LEARNING MATERIALS BASED ON MULTIMEDIA TO INCREASE THE LANGUAGE ABILITY OF AUTISM CHILDREN.

This study aims to producedesign of learning materials based on Multimedia to increase the language ability of autism children class 1 SLB, which adjusted with the needs analysis of autism children in Special Schools Man...

THE CARDIO-PROTECTIVE \"PARAOXONASE-1\" AS A VALUABLE PROMISING TOOL IN DIAGNOSIS AND/OR ASSESSMENT OF CARDIOVASCULAR RISK IN TYPE 2 DIABETES.

Background: Type 2 Diabetes Mellitus \\\\\\\"T2D\\\\\\\"remains frequently undiagnosed for many years; as the hyperglycemia is often not severe enough to provoke noticeable symptoms. Thus, such patients are at increased...

EFFECT OF POLYHERBAL FORMULATION IN THE MANAGEMENT OF SCABIES (PAMA) - A CASE REPORT.

Aim:Skin disease has a high prevalence throughout the world. Scabies is contagious and can spread quickly through close physical contact so it is an acute communicable disease. It is highly prevalent in young children.Th...

THE LEADERSHIP PATTERN STRATEGY OF THE INDONESIAN NAVY (TNI AL) TOWARDS SOLDIERS MOTIVATION IN PEACE MISSION OF THE UNITED STATES (UN)(CASE STUDY OF KRI SULTAN HASANUDDIN-366).

The purposes of this study are 1) analyzing how the motivation of Indonesian Navy soldiers in the KRI Sultan Hasanuddin-366 environment, 2) analyzing the strategy of the leadership patterns of the Indonesian Navy leaders...

A STUDY TO COMPARE EFFICIENCY OF HBA1C, FASTING & POST-PRANDIAL BLOOD GLUCOSE LEVELS, IN THE DIAGNOSIS OF TYPE-2 DIABETES MELLITUS AND ITS PROGNOSTIC OUTCOME.

Background: HbA1C a marker of chronic hyperglycemia, is associated with diabetes and its complications and has been recommended as a diagnostic test. It is an indicator of average blood glucose concentration over the per...

Download PDF file
  • EP ID EP341412
  • DOI 10.21474/IJAR01/7237
  • Views 51
  • Downloads 0

How To Cite

Farhat Ali Lone, Sabha Malik, Shaheera Ajaz, Liaqat Ahmad Malik, Parvaiz Mohiudin Dar. (2018). EVALUATION OF COAGULATION PROFILE IN PATIENTS WITH PREGNANCY INDUCED HYPERTENSION IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL IN NORTH INDIA.. International Journal of Advanced Research (IJAR), 6(6), 501-506. https://europub.co.uk/articles/-A-341412