Evaluation of corneal endothelial cell changes in diabetic patients before and after phacoemulsification surgery: A comparative study
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 4
Abstract
Aim The study was conducted to evaluate and compare the changes in corneal endothelial cell count density ECD and Central corneal thickness CCT between diabetic and non diabetic population before and after phacoemulsification surgerySettings and Design This prospective comparative interventional study was carried out at government medical college and attached group of hospitals a tertiary eye care centre in Rajasthan IndiaMaterials and Methods A total of 50 patients with type II diabetes mellitus age group 3080 years and 50 age matched healthy patients of senile cataract with clear cornea without any other ocular pathology were nonrandomly selected for Phacoemulsification surgery phaco after detailed preoperative assessment All patients were operated by the same surgeon with phaco chop technique to exclude any surgeons related bias Endothelial cell count CCT and Coefficient of Variance CV was measured with specular microscope preoperatively and postoperatively at day 1st 7th 15th 1 month and 3 months seriallyResult Postoperatively the mean ECD was decreased in both the groups but loss of endothelial cell count was significantly more in diabetic population as compare to non diabetic groups at day 1 day 7 day 15 1 month and 3 months CCT was increased on first postoperative day in both the groups subsequently decreased and then returned back to about same as preoperative state after 1 month But postoperatively the change in mean CCT was not significant between both groups The difference in CV was significantly higher in diabetic group as compared to non diabetic group postoperativelyConclusion The corneal endothelial cell changes were significantly high in diabetic population as compared to nondiabetic patients The ECD loss increase in mean CCT and CV were more in diabetic population as compared to non diabetic And patients with diabetes showed slower recovery in endothelial healing as compared to non diabetic groupKeywords Cataract Cornea Central corneal thickness Diabetes Endothelial cell density Phacoemulsification
Authors and Affiliations
Indra Dandaliya, Dinesh Kumar Bedi, Sanjeev K Nainiwal
Keywords
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- EP ID EP474851
- DOI 10.18231/2395-1451.2018.0103
- Views 78
- Downloads 0
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