EVALUATION OF CYTOTOXIC AND GENOTOXIC POTENTIAL OF THE FUNGICIDE RIDOMIL IN ALLIUM CEPA L.
Journal Title: Analele Stiintifice ale Universitatii Alexandru Ioan Cuza din Iasi, Serie noua, Sectiunea II a. Biologie vegetala - Year 2014, Vol 60, Issue 1
Abstract
The cytogenetic effects exerted by the systemic fungicide mefenoxam and copper hydroxide (the active ingredients of Ridomil Gold Plus 42,5 WP fungicide) were studied in root tips of Allium cepa L. A progressive concentration- and time-related inhibition of the mitotic activity of meristematic cells was observed. The mitotic index was minimum (3.38%) at the highest concentration (1500 ppm) of the fungicide tested. The genotoxicity of the fungicide was measured by using the frequency of chromosomal aberrations. The highest percent of abnormal cells (8.39%) were determined for the lowest concentration of 100 ppm of Ridomil. The high frequency of sticky chromosomes, laggard and multipolarity indicated that the investigated fungicide caused abnormal DNA condensation, abnormal chromosome coiling and inactivation of the spindles, having an aneugenic potential.
Authors and Affiliations
NICOLETA ŞUŢAN, AUREL POPESCU, CRISTINA MIHĂESCU, LILIANA SOARE, MARIA MARINESCU
Keywords
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