Evaluation of Dopamine Receptor Integrity after Sevoflurane Exposure in Neonatal Rat Brain Using Positron Emission Tomography
Journal Title: Global Journal of Anesthesiology - Year 2018, Vol 5, Issue 1
Abstract
Aims: The volatile general anesthetic sevoflurane is commonly used across all ages in the clinic. Sevoflurane-induced neurotoxic effects on the developing dopaminergic system are still unclear. The aim of this study was to evaluate the integrity of the D2/D3 receptor in developing rat brain utilizing molecular imaging techniques.
Authors and Affiliations
Q Yin, MG Paule, TA Patterson, F Liu, CM Fogle, SM Apana, M Berridge, W Slikker, C Wang, X Zhang
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