Evaluation of efficacy and safety of intra-articular hylan G-F 20 injection in knee osteoarthritis in patients with repeat injection
Journal Title: International Journal of Orthopaedics Sciences - Year 2017, Vol 3, Issue 3
Abstract
Objective: To evaluate efficacy and safety of intra-articular hylan G-F 20 injection in patients with knee osteoarthritis. Material and methods: In this prospective study, pain relief in adult patients with mild to moderate knee osteoarthritis treated with repeat injection of intra-articular hylan G-F 20 (6 ml) was assessed by visual analoge scale (VAS). Difference in pain relief at six months and one year of treatment was measured. Change in the pattern of analgesic use and type of medications used for pain relief were recorded. Results: Twenty four patients (mean age 56.5 years; 45.83% male) were included. VAS score reduced significantly from 70.42+8.06 at baseline to 22.92+6.24 after six months (p<0.05) and 36.67+8.16 after 12 months (p<0.05). At baseline, 21 (87.50%) patients required two tablets of analgesics daily. After six months of treatment 12 (50%) patients did not require any oral analgesics. After one year of treatment number of patients taking two to three tablets per week were (29.17%). After the mean period of 14.21 (+1.72) years repeat injection was required. Conclusion: Six ml intraarticular hylan G-F 20 provides effective pain relief in patients with mild to moderate knee osteoarthritis for slightly over one year and reduces requirement of analgesics.
Authors and Affiliations
Dr. Nataraj AR, Dr. Sreenivas T, Dr. Jyothi Naik
Keywords
Related Articles
- EP ID EP502576
- DOI 10.22271/ortho.2017.v3.i2j.98
- Views 108
- Downloads 0
Retrospective critical analysis of treatment of closed extra capsular proximal Femur fractures with proximal femur nail at rural teaching setup
Background: For extracapsular proximal femur fractures, the treatment options are innumerous, though the implant choice is debatable. In our institute we use proximal femoral nail for the treatment of extracapsular proxi...
A Prospective study on the surgical management of medial malleolar fractures of ankle joint
Malleolar fractures are the most common ankle injuries treated by orthopedic surgeons. Objectives: The present study was undertaken to study the functional outcome of surgically managed medial malleolar fractures of ankl...
Functional outcome of distal tibia fractures managed with anatomical locking plates
Background: Distal tibia fractures accounts for almost 10% of all tibial fractures. This injury is most frequent in middle aged group probably resulting due to high energy trauma. Optimal fixation with due respect to sca...
Functional outcome of management of lower lumbar (L-3 to L-5) burst fractures: A multicentre study of 34 cases
Aim and Objective: Lower lumbar burst fractures are rare entity with most of the literature restricted to small case series. There is no clear cut consensus on the guidelines for management. Here we present functional re...
A clinical study of minimal invasive anterior bridge plating for humerus shaft fractures
Introduction: In humeral shaft fractures management anterior bridge plating is reported as an acceptable less traumatic and reproducible procedure by several authors. Our study done to evaluated the clinical, radiologica...