Evaluation of efficacy of Amoxicillin plain and Amoxicillin with Clavulanate Acid for treating patients with Odontogenic Space Infections: A Comparative Study

Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 6

Abstract

Background: One of the most common diseases in the oral cavity is Odontogenic infections. With the advent of modern antibiotics, mortality rates have significantly reduced. Such infections are usually self-limiting; purulent material may occasionally burrow deep into fascial spaces. Hence; we planned the present study to assess and compare the effectiveness of amoxicillin plain and amoxicillin with clavulanate acid in treating patients with odontogenic space infections. Materials and methods: The present study included evaluation and comparison of effectiveness of amoxicillin plain and amoxicillin with clavulanate acid in treating patients with odontogenic space infections. A total of 64 patients were included in the present study. Random division of all the patients was done into two study groups, with 32 patients in each group, as follows: Group 1- included patients who were given five hundred mg of amoxicillin for seven days, Group 2- included patients who were given six hundred twenty five mg of Amoxicillin plus Clavulante acid for seven days. On the follow-up visits, we carried out clinical inspection for assessing the pain and inflammation which were graded on a scale of zero to four. Zero score represented absent of inflammation, while four score represented absence of improvement in inflammation. Results: In the present study, we analyzed a total of 64 patients with odontogenic space infection and broadly divided them into two study groups; Group 1 and group 2. Non-significant results were obtained while comparing the number of subjects in each group graded on the basis of inflammation. Conclusion: Both the antibiotics have equal efficacy in treating patients with positive space infection.

Authors and Affiliations

Sumera Gul, Manzoor Mohd Dar, Abdul Latief Najar, Shahid Farooq, Shamina Kosar

Keywords

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  • EP ID EP545532
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How To Cite

Sumera Gul, Manzoor Mohd Dar, Abdul Latief Najar, Shahid Farooq, Shamina Kosar (2018). Evaluation of efficacy of Amoxicillin plain and Amoxicillin with Clavulanate Acid for treating patients with Odontogenic Space Infections: A Comparative Study. Journal of Advanced Medical and Dental Sciences Research, 6(6), 92-95. https://europub.co.uk/articles/-A-545532