Evaluation of efficacy of Amoxicillin plain and Amoxicillin with Clavulanate Acid for treating patients with Odontogenic Space Infections: A Comparative Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 6
Abstract
Background: One of the most common diseases in the oral cavity is Odontogenic infections. With the advent of modern antibiotics, mortality rates have significantly reduced. Such infections are usually self-limiting; purulent material may occasionally burrow deep into fascial spaces. Hence; we planned the present study to assess and compare the effectiveness of amoxicillin plain and amoxicillin with clavulanate acid in treating patients with odontogenic space infections. Materials and methods: The present study included evaluation and comparison of effectiveness of amoxicillin plain and amoxicillin with clavulanate acid in treating patients with odontogenic space infections. A total of 64 patients were included in the present study. Random division of all the patients was done into two study groups, with 32 patients in each group, as follows: Group 1- included patients who were given five hundred mg of amoxicillin for seven days, Group 2- included patients who were given six hundred twenty five mg of Amoxicillin plus Clavulante acid for seven days. On the follow-up visits, we carried out clinical inspection for assessing the pain and inflammation which were graded on a scale of zero to four. Zero score represented absent of inflammation, while four score represented absence of improvement in inflammation. Results: In the present study, we analyzed a total of 64 patients with odontogenic space infection and broadly divided them into two study groups; Group 1 and group 2. Non-significant results were obtained while comparing the number of subjects in each group graded on the basis of inflammation. Conclusion: Both the antibiotics have equal efficacy in treating patients with positive space infection.
Authors and Affiliations
Sumera Gul, Manzoor Mohd Dar, Abdul Latief Najar, Shahid Farooq, Shamina Kosar
Keywords
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