Evaluation of Factors Affecting Perioperative Mortality in Newborns with Critical Congenital Heart Disease
Journal Title: Journal of Academic Research in Medicine - Year 2020, Vol 10, Issue 1
Abstract
Objective: Congenital heart diseases (CHD) are most common malformation group in neonatal period and their frequency ranges from 6 to 8 in 1.000 live births. Critical CHD constitutes approximately 25% of group and results in mortality if not diagnosed and treated in neonatal period. The aim of our study was to determine the factors affecting the perioperative mortality of patients with critical CHD. Methods: Our study was performed retrospectively between July 2017 and December 2018. The demographic data, echocardiographic diagnosis and comorbidities of the patients were recorded. Patients who were discharged and who were dead were compared in terms of risk factors. In the descriptive analyses, the student’s t-test was used for normally distributed numerical variables and the Mann-Whitney U test was used for non-normally distributed variables. Categorical variables were presented in percentages and by using cross tables. Results: Ninety-two cases were included in the study, 19 were premature and 16 had additional organ anomalies, 23.9% had low birth weight. The rate of antenatal diagnosis was 39.1% and 14.1% of the cases needed resuscitation in the delivery room. During admission, 41 cases needed inotropic agent. Low birth weight, prematurity, resuscitation need, additional organ anomaly and need for inotropic support were found to be statistically significant in the mortality group (p=0.027, 0.026, 0.001, 0.001, 0.022, respectively). Conclusion: Prematurity, low birth weight, and additional organ anomalies are critical risk factors for cardiac malformation. In addition, patients with active cardiopathy during intrauterine period are more resuscitated in the delivery room, their inotropic needs are higher, and they have higher mortality.
Authors and Affiliations
Adil Umut Zübarioğlu, Özgür Yıldırım, İsmail Balaban, Shıraslan Bakhshalıyev, Cenap Zeybek
Keywords
Related Articles
- EP ID EP684378
- DOI 10.4274/jarem.galenos.2019.2832
- Views 178
- Downloads 0
Do INI1 and E-cadherin Expression Loss Have Any Significance in Endometrial Carcinomas?
Objective: Endometrial carcinoma (EC) is a highly heterogeneous malignancy in terms of morphology, clinical course, response to treatment and prognosis. This study aimed to investigate the loss of INI1 (SWI/SNF family me...
Cervical Lipoleiomyoma: Case Report
Lipoleiomyomas are uncommon benign neoplasms composed of various mixtures of long intersecting bundles of bland smooth-muscle cells and mature adipocytes. These tumors are most commonly located in the uterine corpus, but...
Outcomes of Post-traumatic Stiff Elbow Arthrolysis
Objective: In this study, the results of open release surgeries performed for the stiff elbows which were caused by intrinsic, extrinsic or by combination of both factors were evaluated. Methods: Twenty-three elbows of...
Is the Probiotic Mixture Effective in the Treatment of TNBS-induced Experimental Colitis?
Objective: Inflammatory bowel disease (IBD) is an idiopathic disease associated with changes in the immune system and in the intestinal microbiota. The most accepted hypothesis of IBD pathogenesis is thought to be the ab...
Does Hair Strand Cause Failure of Sterilization? A Controlled Experimental Study
Objective: Besides the standard applications of surgical aseptic techniques, it is known that different teams display different approaches in the presence of a hair strand in sterile packs. Few of the teams prefer not to...