EVALUATION OF FICUS RACEMOSA LEAF FOR WOUND HEALING ACTIVITY
Journal Title: International Journal of Pharmacognosy - Year 2016, Vol 3, Issue 12
Abstract
The wound healing activity of leaves of Ficus racemosa Linn. alcoholic, chloroform and ethyl acetate extract ointments were evaluated on wistar rats by excision wound model for a period of 12 days and incision wound model for a period of 10 days. In incision model the parameter carried out was tensile strength of wounded skin. In excision model percentage wound contractions were determined for all the groups. Reference standard drug was curcumin ointment. Animals treated with extracts of Ficus racemosa Linn. showed marked reduction in wound area in comparison to control group from 4th day onwards. From the observations, it is found that in both the models, alcoholic extract of Ficus racemosa and enriched diet was have greater wound healing activity in terms of tensile strength in incision model and percentage wound closure, in excision model than that of other groups. Enriched diet also showed good wound healing activity which may be due to high protein content and fatty acids present in oil.
Authors and Affiliations
Lavanya et al.
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