Evaluation of histomorphological findings and malignancies in postmenopausal bleeding

Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2

Abstract

Introduction In this era as the life expectancy is increasing women are experiencing a long postmenopausal phase Postmenopausal bleeding PMB is a sinister complaint and accounts for about 10 of postmenopausal complaints Being a symptom of varied etiologies and its strong association with malignancy it should be diligently evaluatedAims and Objectives 1 To evaluate the histopathological spectrum of lesions presenting as PMB 2 To estimate the incidence of premalignant and malignant lesions presenting as PMB 3 To confirm the benign nature of the lesions to prevent unnecessary radical treatmentMaterials and Methods This prospective study done from January 2016 to September 2017 and included the endometrial biopsiescurettages and cervical biopsies sent for histopathological examination from clinically diagnosed cases of postmenopausal bleedingResults Out of all the samples majority were benign lesions 44 followed by premalignant 257 malignant lesions 183Conclusion A variety of histopathological findings are seen in PMBBenign pathologies were more common in our study but the collective proportion of premalignant and malignant lesions is considerably higher in this studyAccurate diagnosis makes it much easier to counsel the patient about further course of management prevent unnecessary radical treatment for benign conditions prompt treatment and vigilant follow up for malignant lesionsKeywords Postmenopausal bleeding PMB Endometrial carcinoma Histopathology

Authors and Affiliations

M. Pavani, Ch. Geetha, L. Peter Ericson, Ashok Kumar Deshpande

Keywords

Related Articles

Placental pathology in low birth weight babies a prospective observational study

Introduction Low birth weight LBW babies are more common in developing countries like India The placenta is an organ which connects fetus to mother during intrauterine life Any change in the mother reflects on placenta a...

Histopathological study of ovarian tumours

Ovarian tumours are common neoplasms in females and have diverse histopathological entities as they are derived from different cells of origin Histopathological patterns and incidence of 121 ovarian tumours were studied...

Synchronous fibroepithelial tumors and carcinoma of the breast

Introduction: Fibroadenoma and phyllodes tumor are fibroepithelial neoplasms of the breast composed of proliferating mammary epithelial and stromal tissues.It is very rare for infiltrating ductal carcinoma to arise withi...

Bilateral mature cystic teratoma of ovary: A rare case presentation

Mature cystic teratomas are ovarian neoplasms derived from two to three germ cell layers ie ectoderm mesoderm and endoderm Ovarian teratomas are usually benign tumours of the reproductive age group They usually have righ...

Diagnostic efficacy endometrial aspiration cytology in gynecological pathology

Introduction: Endometrial aspiration cytology is a diagnostic modality for studying cyto-harmonal changes and for evaluating endometrial pathology ranging from inflammatory changes, hyperplasia and endometrial malignanci...

Download PDF file
  • EP ID EP475507
  • DOI 10.18231/2394-6792.2018.0057
  • Views 33
  • Downloads 0

How To Cite

M. Pavani, Ch. Geetha, L. Peter Ericson, Ashok Kumar Deshpande (2018). Evaluation of histomorphological findings and malignancies in postmenopausal bleeding. Indian Journal of Pathology and Oncology, 5(2), 302-307. https://europub.co.uk/articles/-A-475507