Evaluation of Histopathological Changes in Gallbladder Mucosa in Relation to Gallstones with Duration
Journal Title: GJRA-Global Journal For Research Analysis - Year 2015, Vol 4, Issue 3
Abstract
Gallstone diseases are very common throughout the world including India. It is estimated that between 85% and 90% of patients who have gallstones remain asymptomatic and less than 20% chance to develop symptoms. There have risk of disease related complications such as acute cholecystitis, gallstone pancreatitis and choledocholithiasis. The present study was conducted on 100 patients of gallbladder diseases irrespective of gender aged between 11 to 65 years. Out of 100 patients cholecystectomy was carried out on 87 patients. 13 patients of gallbladder disease left the hospital before their full work-up. The histopathological evaluation revealed that 44 cases (50.57%) were having only chronic cholecystitis with cholelithiasis, 18 cases (20.69%) were of acute on chronic cholecystitis with cholelithiasis, 13 cases (14.94%) were of Chronic cholecystitis with cholelithiasis with Metaplasia of gallbladder mucosa, 9 cases (10.34%) were of Chronic cholecystitis with cholelithiasis with Dysplasia of gallbladder mucosa,3 cases (3.45%) were of Chronic cholecystitis with cholelithiasis with Carcinoma gallbladder (Adenocarcinoma). Prophylactic cholecystectomy can be offered to patients having asymptomatic cholelithiasis as there is high incidence of gallstone related complications including carcinoma gallbladder.
Authors and Affiliations
Mohd. Arshad Raza, Jagadamba Sharan, Chandra Prakash Pandey, M. D. Tripathi
Keywords
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