Evaluation of hs-CRP levels in acute coronary syndromes
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 6
Abstract
Background: The incidents of CAD is increasing alarmingly and evidence is emerging about the role of novel risk factors. hs-CRP is emerging as a crucial risk factor for premature atherothrombosis and cardio vascular events. Elevated hs- CRP concentrations early in Acute Coronary Syndrome (ACS), prior to the tissue necrosis, may be a surrogate marker for cardiovascular co-morbidities. Aim: This study was undertaken to measure the levels of serum hs-CRP in patients with CAD as established by CAG. Materials and methods: This study included 100 patients admitted in General Medicine and Cardiology departments with a spectrum of coronary artery disease and undergoing coronary angiography. Routine blood investigation, ECG, Chest cardiograph, and 2D Echo test were performed. Results: A total 100 patients established that hs-CRP were elevated in all the patients irrespective of risk factor status. Also there was statistically significant difference between the levels of hs-CRP and angiographic extent of lesion. hs-CRP levels were also found to be higher in in patients with positive family history of CAD and elevated LDL-C, decreased HDL-C. Conclusion: measurement of hs-CRP should not be used as an alternative for but as an adjunct to major risk factors in assessing and thus better define the intensity of preventive therapies to be initiated.
Authors and Affiliations
R. S. Pushpa Kumari, Priya John, V. A. Vipula
Keywords
Related Articles
- EP ID EP428802
- DOI -
- Views 112
- Downloads 0
Thrombolysis for stroke in a tertiary care center from Hyderabad
Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) within 4.5 hours of symptom onset is currently approved for treatment of acute ischemic stroke. It improves the rate of favourable...
Symptomatic Pulmonary Siderosis – A case report
Pulmonary siderosis or Welder’s lung is a rare occupational lung disease which occurs due to long term inhalation of iron compounds. It is most commonly seen in arc-welders. Most of the patients are asymptomatic with mil...
A comparative study of the effect of dexmedetomidine and lignocaine on hemodynamic and airway responses following extubation
Background: Dexmedetomidine is the newer highly selective alpha 2-adrenoreceptor agonist. It has sympatholytic, sedative and analgesic properties with no respiratory depression. Various studies have evaluated the usefuln...
Assessment of audiologic evaluation in patients with acquired hypothyroidism
Introduction: Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone or, more rarely, from their impaired activity at tissue level. In its clinically overt form, hypothyroidism is a re...
Clinical study of Hashimoto’s thyroiditis
Background: Hashimoto’s thyroiditis, a well known condition affecting the thyroid gland is often under diagnosed due to its wide spectrum of clinical manifestations. As such it could present as a Multi Nodular Goitre, Di...