Evaluation of hsCRP, Insulin and Insulin resistance in Polycystic Ovarian Syndrome
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Polycystic Ovarian Syndrome consists of a constellation of metabolic abnormalities and is now well recognised having a major effect throughout life on the reproductive, metabolic and cardiovascular health of affected women. Objective: The present study was conducted to evaluate hsCRP, insulin and insulin resistance levels in PCOS patients. Materials and Method: 30 PCOS subjects in the age group of 18 to 34 years and 25 age-matched healthy women as controls were evaluated. Result: Serum hsCRP, insulin, insulin resistance, BMI and waist-to-hip ratio were significantly elevated (p<0.0001) in PCOS cases when compared with controls. There was a positive correlation between hsCRP and insulin (p=0.2001) and hsCRP and insulin resistance (p = 0.127) in PCOS patients. Conclusion: PCOS women have added risk of complications of cardiovascular disease and Diabetes mellitus.
Authors and Affiliations
Sapna Jangir, Jairam Rawtani
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