Evaluation of IL-22 polymorphism in patients with visceral leishmaniasis
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2014, Vol 4, Issue 0
Abstract
Objective: To examine the IL-22 gene polymorphism in visceral leishmaniasis (VL) patients in comparison to healthy people as the control group. Methods: The blood samples were collected from 236 people, among them 74 were patients with a history and clinical symptoms of leishmaniasis and 162 were healthy with no signs of infection and all of them were residents in endemic area of VL in East Azerbaijan Province. DNA extraction was performed by using salting out method and amplification refractory mutation system-polymerase chain reaction was used for detecting the polymorphism of IL-22 promoter (rs2227473A/G). Results: In patients group, 9 (12.16%) individuals showed A/A genotype and 29 (39.18%) showed G/ G genotype. The heterozygote form (A/G) was 36 (48.64%) among this group. In the control group, the proportions of genotypes were 8.02%, 46.09% and 45.06%, respectively. Conclusions: According to our results, there was no significant association between VL and polymorphism of IL-22 gene promoter (rs2227473A/G).
Pharmacognostical and quality control parameters of Stellaria media Linn.
Objective: The present study was attempted to evaluate the pharmacognostical and quality control parameters of Stellaria media Linn. Method: The plant was studied for taxonomic characters, standardization parameters viz....
HPTLC fingerprint profile of Bauhinia variegata Linn. leaves
Objective: To develop the finger print of medicinally and economically important leaves of Bauhinia variegata Linn. Methods: Ethanol extract of the leaves were developed in the mobile phase of n-Hexane: Ethyl acetate: Fo...
Surveillance of tuberculosis co-infection among HIV infected patients and their CD4+ cell count profile
Objective: To determine the occurrence of tuberculosis (TB) among HIV infected patients and their CD4+ cell count profile. Methods: A total of 263 HIV-seropositive patients either hospitalized or reporting to the antiret...
Internal hirudiniasis in a hen (Gallus gallusdomesticus)-The first report in literature
The leech is a blood sucking worm belonging to the class Hirudinea of the phylum Annelida. Leeches are commonly found in the waterland of temperate and tropical countries. Hirudiniasis, a rare condition with unusual symp...
Effect of temperature, rainfall and relative density of rodent reservoir hosts on zoonotic cutaneous leishmaniasis incidence in Central Tunisia
Objective: To study the effect of climate variability and rodent density on the incidence of zoonotic cutaneous leishmaniasis (ZCL) in humans. Methods: We collected monthly ZCL human cases in primary health care faciliti...