EVALUATION OF IN-VITRO MEMBRANE STABILIZATION AND THROMBOLYTIC ACTIVITIES OF RAVENALA MADAGASCARIENSIS SONN
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 10
Abstract
The aim of the present study was to evaluate the in-vitro membrane stabilization and thrombolytic activities of the methanolic extracts of root and leaves of Ravenala madagascariensis Sonn. Assessment of in-vitro membrane stabilization activity was carried out by hypotonic solution induced hemolysis method in which both root and leaves extracts along with the standard drug acetyl salicylic acid, significantly (p<0.0001) inhibited hemolysis when compared to control. For illustration, root and leaves extracts caused maximum inhibition of hemolysis of 39.21% and 30.75% respectively. In in-vitro thrombolytic activity test, 39.29% and 22.96% clots were lysed by root and leaves extract respectively which were also of statistical significance (p<0.0001).
Authors and Affiliations
Md. Abul Hassan
Keywords
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