Evaluation of Intracranial Ring Lesions by Diffusion-Weighted Imaging and in Vivo Proton Magnetic Resonance Spectroscopy
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 11
Abstract
AIMS & OBJECTIVES: To assess the combined role of diffusion weighted imaging and spectroscopy in differentiating ring enhancing intracranial cystic lesions. MATERIALS AND METHIODS: The study was conducted from Oct 2011 to Sep 2013. Thirty (30) patients having ring enhancing intracranial cystic lesions were included in the study. 1.5 tesla MRI ACHEIVA (Phillips) with routine MRI sequences with diffusion weighted imaging (DWI) and ADC mapping followed by ADC value in the center of lesion was used. Proton Magnetic resonance spectroscopy was performed on these patients followed by T1W contrast. The radiological diagnosis was correlated with histopathological examination in 12 patients and the remaining were evaluated clinical parameters and blood tests by the clinicians. RESULTS: Infective lesions were characterized by decreased Ch/NAA and decreased/ near normal Ch/Cr ratio as compared to ring enhancing cystic neoplastic lesions. Elevated lactate and lipid peaks were found to be characteristic for Tuberculomas. Cystic neoplastic lesions could be differentiated from infective lesions. Cerebral abscesses differed on the basis of elevated lactate and amino acid peaks. Brain abscesses showed high signal intensity in DWI and reduced ADC in the centre of lesion as compared to cystic neoplastic lesions. CONCLUSIONS: The combined role of MRI with MRS and Difusion weighted imaging is found to be useful in accurate evaluation and differentiation of intra cranial cystic ring enhancing lesions. Reduced ADC value with diffusion restriction is highly suggestive of brain abscess while in absence of restriction; magnetic resonance spectroscopy is useful in distinguishing abscess from other infective lesions and cystic neoplasms
Authors and Affiliations
Samita Singal
Keywords
Related Articles
- EP ID EP214805
- DOI -
- Views 65
- Downloads 0
Prevalence of various stages of Diabetic Retinopathy in patients of Diabetes Mellitus-Type 2
Introduction: Diabetic eye disease is a leading cause of vision loss in persons aged 20 to 74 years 1 . Diabetes has many manifestations in the eye, of which cataracts and Diabetic Retinopathy (DR) are the most significa...
Evaluation of Significance of Total Bilirubin and C-Reactive Protein in Suspected Cases of Acute Appendicitis
Aims: To evaluate the importance of serum CRP level and Total bilirubin levels in the diagnosis of acute appendicitis, by comparing with final histopathologic diagnosis. Materials and Methods: This study was done in 100...
Clinico Pathological Study of Ovarian Tumors- A Retrospective and Prospective 5 Years Study
Ovarian neoplasms have different cell origin and have various histopathologies. Increased mortality in ovarian malignancies is due to late presentation at advanced stage. During the period of 5 years (June 2011 to June 2...
Effects of Nesiritide in Patients with Acute Decompensated Heart Failure – A Review
Acute decompensated heart failure is a major health problem that is associated with several million hospitalizations worldwide each year. [1] In such patients, the predominant symptoms are dyspnea and fatigue which are a...
Pattern of Help Seeking Behaviour in Female Breast Cancer Patients
Introduction: Incidence of breast cancer has been increasing in Kerala over the past decade and has overtaken cervical cancer. Early detection and treatment can completely cure breast cancer. Delay of more than 3 months...