Evaluation of Ki-67 in Breast Cancer

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3

Abstract

Breast cancer is now the common cause of cancer-related death among women. Proliferation markers in breast cancer seem to be a prognostic factor. Immunohistochemistry of the nuclear antigen Ki-67 is the most common proliferation marker used in studies by the assessment of the percentage of cells staining positive for Ki-67. This study analyzed the association between Ki-67 index and clinical parameters, histopathological parameters and intrinsic subtypes of breast cancer. A higher Ki-67 index correlated significantly with young age, larger tumors, and positive lymph nodes.

Authors and Affiliations

Arumugam Velappan, Deepa Shunmugam2

Keywords

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  • EP ID EP600156
  • DOI 10.9790/0853-1603095964.
  • Views 71
  • Downloads 0

How To Cite

Arumugam Velappan, Deepa Shunmugam2 (2017). Evaluation of Ki-67 in Breast Cancer. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 16(3), 59-64. https://europub.co.uk/articles/-A-600156