Evaluation of Ki-67 in Breast Cancer
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Breast cancer is now the common cause of cancer-related death among women. Proliferation markers in breast cancer seem to be a prognostic factor. Immunohistochemistry of the nuclear antigen Ki-67 is the most common proliferation marker used in studies by the assessment of the percentage of cells staining positive for Ki-67. This study analyzed the association between Ki-67 index and clinical parameters, histopathological parameters and intrinsic subtypes of breast cancer. A higher Ki-67 index correlated significantly with young age, larger tumors, and positive lymph nodes.
Authors and Affiliations
Arumugam Velappan, Deepa Shunmugam2
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