Evaluation of Leptin Levels in Gingival Crevicular Fluid during Orthodontic Tooth Movement.
Journal Title: International Journal of Dental Science and Innovative Research (IJDSIR) - Year 2019, Vol 2, Issue 2
Abstract
Objectives: To test if leptin can be detected in the gingival crevicular fluid (GCF) and to determine whether any changes occur during orthodontic tooth movement. Materials and Methods: Thirty patients were included in the study in which canine retraction was carried out with a NiTi closed coil spring on either side. GCF samples were collected before the commencement of canine retraction, on the first, Six hrs and 21st day after application of force and were analysed for leptin levels by the ELISA technique. An upper canine requiring distal movement served as the test tooth; thecontralateral canine was used as a control tooth. The control tooth was included in the orthodonticappliance,but was not subjected to the retractive orthodontic force. GCF sampling from the distal sites of the test and control teeth was done at baseline, 1 hour, 6hours, and 21st day. Results: Leptin concentrations of the test teeth decreased in a time-dependent manner. When Compared with the baseline measurement, the decrease was stastically significant at 6hrs and 21st day (P <.001)but didn’t reach baseline value explaining inflammatory reactions immediately after forces applied . Conclusions: The concentration of leptin in GCF is decreased by orthodontic tooth movement; the results of the present study also suggest that leptin may have been one of the mediators responsible for orthodontic tooth movement.
Authors and Affiliations
Dr. Seema Pendharkar
Keywords
Related Articles
- EP ID EP579787
- DOI -
- Views 93
- Downloads 0
An Esthetic and Functional Fixed Posterior Space Maintainer-A Case Report.
Introduction Early loss of a deciduous tooth is one of the major causes for development of malocclusion. Space maintainers are the appliances that are custom-made by the dentist to prevent the space loss and its further...
Biopsy of an Innocent Swelling Resulting in a Rare and Unusual Clinical Diagnosis.
Intraoral lesions often present as nodules or swellings. A soft tissue swelling can involve any region of the oral mucosa including gingiva. The primary disease processes that give rise to swellings and tumors of the ora...
Redefining Integrative Biologic Medicine Through Ayurveda. – An Ancient Way.
Oraldiseases are continued to be a major health concern worldwide. Dental caries and periodontal diseases are amongst the most important oral health issues. Oral health is the mirror of general healt...
Comparison of Dimensional Accuracy and Bond Strength of Combined Reversible – Irreversible Hydrocolloid Impression System with the Other Commonly Used Impression Materials – An In Vitro Study
A dimensionally accurate impression is one of the primary determinants for a precise fitting indirect restoration. There are some factors that affect definitive impression quality such as tooth preparation design, soft t...
Electromyography of the Masticatory Muscles – A Quick Glance.
The knowledge of masticatory function and its relationship with craniofacial morphology is essential to the field of orthodontics. Electromyography has been used to assess the muscle function of the masticatory muscles b...