EVALUATION OF NITRIC OXIDE RADICAL SCAVENGING ACTIVITY OF A HEALTH SUPPLEMENT, HERBALONE
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 5
Abstract
Nitric oxide (NO) plays a key role in the production of reactive nitrogen species (RNS). The objectives of this study were to determine antioxidant activities of ethanol extracts of raw materials and product samples were obtained from SNBIO Co. The product name is the HERBALONE. The antioxidant activity of their extracts was measured on the basis of thescavenging activity of nitric oxide radical (NO˙)-scavenging activity. The assay was measured by the Greiss reagent. NO scavenging activity of product samples at 100.0 mg/ml was 14.3%. Overall, thedegree of NO inhibition activity of product sampleswas not high. NO scavenging activity at 100.0 mg/ml was 74.5%. The antioxidant activity for NO-scavenging found on raw materials. Thus, in order to exhibit a similar NO scavengingfunction, the content should be increased by about 5.2 (74.5/14.3) to 20.8 (49.8/2.4) times.
Authors and Affiliations
Man Kyu Huh
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