Evaluation of Occurrence of Medication Errors in Liver Disease Patients
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 4
Abstract
Aim: The aim of this study was to retrospectively review the patient profiles with liver diseases in order to determine the frequency of medication errors among patients with liver diseases. Study Designed: Retrospective study was performed. Place and Duration of Study: Abbasi Shaheed Hospital (ASH), Civil Hospital (CIVIL) and Dow University Hospital (DUH) Karachi Pakistan, conducted from April 2014 to June 2014. Methodology: The retrospective study was conducted by evaluating 61 patient profiles. These patients were admitted in three different hospitals of Karachi city mentioned above. Toxic hepatitis or drug-induced liver injury comprises a spectrum of clinical diseases that initiates with mild biochemical abnormalities and extends to acute liver failure. In this study 61patient’s profiles were collected and evaluated. The patients were aged 25 years and above. A quantitative analysis and investigation of clinically significant drug-drug interactions, drug-disease interactions, inappropriate medication, over dose and sub therapeutic dose has been studied. Moreover these patients were suffering from either hepatitis B, hepatitis C, hepatitis E, ascites, jaundice, liver abscess, hepatoma, chronic liver disease (CLD), cirrhosis, hepatic encephalopathy or acute hepatitis. Results: A total 257 medication errors were observed, out of which 40% (n=102) were drug-drug interactions, 14.5% (n=37) were drug-disease interactions, 37.7% (n=97) were inappropriate medications, 7.05% (n=18) were related to over-dose and 1.17% (n=3) were identified as sub-therapeutic dose errors. The occurrence of different types of medication errors was significantly different among the named hospitals. Conclusion: It can be concluded that a large number of medication errors in a minimal patient’s profiles were observed. This shows a high percentage of irrational prescribing practice among liver disease patients. Furthermore, there is a need to revise the proper structure of hospital and clinical pharmacies. Additionally, the proper prescribing patterns should be followed via employing computerized physician order entry system (CPOE).
Authors and Affiliations
Sumbul Shamim, Shumaila Shafique
Keywords
Related Articles
- EP ID EP348144
- DOI 10.9734/BJMMR/2015/17488
- Views 67
- Downloads 0
Predicting Recurrence in Cervical Cancer Patients Using Clinical Feature Analysis
The paper demonstrates an analytic approach for prediction of recurrence in the cervical cancer patients using a probabilistic model. The techniques used for classification and prediction are based on recognizing typi...
A Rare Cause of Recurrent Epistaxis: Lobular Capillary Haemangioma
Nasal lobular capillary haemangiomata are rare benign nasal tumours of vascular origin and unknown etiology. They tend to occur in both sexes depending on the age group. They usually present with unilateral nasal obstruc...
Prevalence of Lower Urinary Tract Symptoms in Apparently Healthy Young Nigerian Women
Aim: Lower urinary tract symptoms (LUTS) are common in the general population, compromise quality of life and may result in increased health care costs for the society. We observed that many of the studies previously pub...
Buruli Ulcer Disability in Ghana: The Problems and Solutions
Buruli ulcer (BU) is a tropical disease caused by Mycobacterium ulcerans (M. ulcerans) but with “unknown” means of transmission. In order to help reduce this disease, many preventive and treatment measures have been reco...
On Which Variable(s) Should We Condition to Remove Confounding Bias?
Using causal diagrams and an axiomatization of causality, we examined the well-known claim that conditioning on confounders (“adjustment” for confounders) is sufficient to remove confounding bias. We show that this advic...