Evaluation of oxidative stress markers in infertile women
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 10
Abstract
Reproductive failure is a significant public health concern. Recently, ROS have been shown to have an important role in the normal functioning of the reproductive system and in the pathogenesis of infertility in females. Oxidative stress affects both natural and assisted infertility. Treatment that reduces OS may help infertile women with the disease that is caused by imbalance between free radicals and antioxidants. MDA is an end product of lipid peroxidation which can be used as a biomarker to measure the level of oxidative stress. TAC measures the low molecular weight non enzymatic antioxidants. Increase in MDA and decrease in TAC indicates an increase in oxidative stress. In the present study, it was observed that there was a statistically significant increase in serum MDA levels in female factor infertility and unexplained infertility when compared to controls. There was a statistically significant decrease in serum TAC in female factor infertility and unexplained infertility when compared to controls and statistically significant increase in serum LDH in infertile women with unexplained infertility compared to the control group and female factor infertility signifying the apoptotic damage in the unexplained infertility.
Authors and Affiliations
Rajeshwary P, M. Nagaprasanth, Salma Mahaboob R, G. Obulesu
Impact of Lactation Counseling To Mothers on Breast Feeding Practices
Background: Breastfeeding is the healthiest way to feed a baby. Like mothers love there is no substitute for breast milk. Despite of benefits of breast feeding, the breast feeding incidence and the duration of exclusive...
Scrutiny of extent of axillary node dissection for patients with primary breast cancer
Background: Carcinoma of the breast is the most common of non-skin malignancies in women and is second to lung cancer is a cause of cancer deaths. A woman who lives to age 90 has a one in eight chance of developing breas...
Single dose amoxicillin induced toxic epidermal necrolysis – A rare life threatening dermatological condition
Toxic epidermal necrolysis is a severe cutaneous drug reaction, mainly involving skin and mucous membranes. We have presented here a case report of 16 year old female patient who was diagnosed with toxic epidermal necrol...
Raised serum uric acid levels as an independent risk factor for the development of hypertension
Background: Raised serum uric acid has been reported to be associated with an increased risk of coronary heart disease and is commonly encountered with essential hypertension, even untreated hypertension, and type 2 diab...
Serum concentration of 25-hydroxy vitamin D in psoriatic patients in a tertiary care hospital - A case control study
Background: Vitamin D is a fat soluble vitamin and synthesized by skin from 7-dehydroxy cholesterol during exposure to UV-B. Vitamin D is essential for calcium homeostasis, bone growth and immune regulation. Vitamin D de...