Evaluation of Platelet Count and Platelet Indices and Their Significance in Pre-Eclampsia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
Preeclampsia is a common medical complication of pregnancy. It is one of the leading cause of maternal and foetal morbidity and mortality. Several studies have demonstrated the relationship between platelet indices and preeclampsia with variable results. To evaluate the relationship between platelet count and platelet indices and their significance in preeclampsia. To study the platelet count and indices in preeclampsia and compare to normal pregnant women and to study their role in diagnosis of severity of preeclampsia. This study was a prospective case control study done over a period of two years in a tertiary care Hospital and Research centre, Pune. Study comprised of 200 pregnant women of which 100 were normotensive and 100 had preeclampsia (mild to moderate grade:89, severe grade:11). Blood samples were analysed for platelet count and indices in both groups and results were compared. Platelet count decreased and platelet indices like Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), Platelet Large Cell Ratio (P-LCR) were significantly increased in preeclampsia as compared to normotensive women. Platelet count decreased and platelet indices increased in severe grade of preeclampsia as compared to mild-moderate grade however there was no statistical significant difference. Platelet count and indices can be used for early detection of preeclampsia. Rise in platelet indices suggests increased severity of preeclampsia which alerts physician for close management of the patient.
Authors and Affiliations
Dr. Archana Chirag Buch, Dr. Amardeep Ajinath Patil, Dr. Neekita Shriram Agrawal, Dr. Kunjal Mukesh Karia, Dr. Manpreet Kaur, Dr. Namrata Patro
Keywords
Related Articles
- EP ID EP485347
- DOI -
- Views 49
- Downloads 0
The Study of Serum Calcium and Vitamin D Levels in Preeclampsia and Pregnancy Induced Hypertension
Abstract: Recent evidences suggest a high prevalence of calcium and vitamin D deficiencies in preeclamptic women. However, level of these parameters in pregnancy induced hypertension has not been studied thoroughly. So t...
Study of Clinico-Radiological Risk Factors and Laboratory Parameters in Association with Post Stroke Vascular Cognitive Impairment
Abstract: Cognitive impairment due to cerebrovascular disease is termed.” vascular cognitive Impairment “(vici,) and forms a spectrum that includes vascular dementia and milder forms of cognitive impairment referred to a...
Dexmedetomidine for Prevention of Propofol Induced Pain: A Prospective, Randomized, Double Blind Controlled Study
Abstract: Propofol, an intravenous (IV) anesthetic is associated with pain on injection with incidence ranging from 28% to 90% in adults. The aim of present study is to know the anti-nociceptive effect of dexmedetomidine...
Socio-demographic Profile of Pregnancy Induced Hypertension in a Tertiary Care Centre
Pregnancy induced hypertension complicates approximately 6% of pregnancies globally and is the most important cause of maternal and neonatal morbidity and mortality. In our prospective case-control study, socio-demograph...
Profile of Assault Victims Attending an Emergency outpatient department of a Teaching Hospital in India
Studies pertaining to the magnitude and pattern of assault related injuries in Northern India are few. The aim of this study is to assess the epidemiology and details of injuries sustained by assault victims. A prospecti...