Evaluation of Prevalence and Causes of Acute Kidney Injury and its Effect on Short Time Mortality in Intensive Care Unit Patients
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 10
Abstract
Introduction: Hospital mortality of Intensive Care Unit (ICU) patients has shown correlation with severity of the Acute Kidney Injury (AKI). There are a few studies regarding short term or long term morbidity and mortality of the ICU patients after hospital discharge. Aim: The aim of the study was to evaluate predisposing factors, in hospital mortality and six months followup of the ICU admitted patients in two general hospitals. Materials and Methods: This prospective descriptive study was carried out on 520 ICU admitted patients, in Hajar and Kashani Hospitals, Shahrekord, Iran. The patients were evaluated for causes of hospital admission and inpatient and outpatient mortalities three and six months after discharge. Data were collected and analyzed by SPSS version 19.0 through Spearman’s and Pearson’s correlation tests. Results: Of 520 patients under study, 350 were male and others were female. Mean age of the patients was 55.06±23.3 years. During ICU admission, AKI developed in 147 (28.2%) patients. Based on RIFLE criteria, in the patients with AKI, prevalence of risk, injury and failure were 51 (35%), 44 (30%) and 52 (35%) patients respectively. In the patients older than 65, AKI was more common (p=0.03). In the patients with AKI compared to other patients, serum sodium (Na), Potassium (K), was higher but haemoglobin and platelet were significantly lower. During ICU admission 91 (17.5%) patients died, out of which 56 (38%) cases had AKI and 35 (9.3%) had not (p<0.001). Among dead patients, prevalence of risk, injury and failure were 16%, 30.3% and 53.5% respectively. Among the alive patients, after hospital discharge, 3 months survival were 55.1%, 54.9%, 46.8% and 68.9% in risk, injury, failure and non AKI groups respectively (p=0.002), however six months survival of the AKI patients were 54.7%, 46.3% and 24.9% in risk, injury and failure patients comparing to 69.2% in non AKI patients respectively (p=0.001). Conclusion: The study showed that inpatient mortality and short term survival of the ICU admitted patients had correlation with severity of AKI, based on RIFLE criteria. So, proper prophylaxis and treatment methods for prevention of AKI are very important and critical in these patients.
Authors and Affiliations
Ali Momeni, Fereidun Khaje Ali, Bahareh Behvandi, Foruzan Ganji
Keywords
Related Articles
- EP ID EP364773
- DOI 10.7860/JCDR/2017/21575.10722
- Views 52
- Downloads 0
Synchronous Neuroendocrine Tumour of Small Intestine in a Case of Squamous Cell Carcinoma Cervix–An Incidental Finding
Multiple Primary Cancers (MPCs) are defined as two or more malignancies in a single individual without any relationship between cancers. Neuroendocrine carcinoma is a relatively rare tumour and its coexistence with other...
A Study on Chronic Proton Pump Inhibitor Usage and Small Intestinal Bacterial Overgrowth (SIBO)
ABSTRACT Introduction: Small Intestinal Bacterial Overgrowth (SIBO) has a wide clinical spectrum, and may be associated with both maldigestion and malabsorption. Proton Pump Inhibitors (PPI) are one of the most widely pr...
Histomorphological Study of the Endometrium in Response to Insulin Resistance Induced by High Energy Diets in Swiss Albino Mice
ABSTRACT Introduction: The morphology of endometrium is continuously influenced by hormones in each menstrual cycle. In addition to this, metabolic syndrome such as obesity and insulin resistance affects the morphology o...
Protein Creatinine Index: An Alternative for Screening Nephropathy in Hypertensives
ABSTRACT Introduction: The 24 hour urinary protein estimation is the gold standard for detecting proteinuria and nephropathy in hypertensives. But, it’s a time-consuming and inconvenient process. Aim: To analyse the util...
Correlation between Maxillary Canine Calcification and Skeletal Maturation
Introduction: Skeletal maturation assessment has a great role in many health professions especially in Orthodontics & Dentofacial Orthopedics. Functional appliances have proved to be more effective when used at the peak...