Evaluation of Prevalence Pattern of Vitamin D Deficiency in Known Population- An Observational Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 3
Abstract
Background: In adults, chronic vitamin D deficiency leads to osteoporosis, osteomalacia, muscle weakness and increased risk of falls and fractures. The present study was conducted to assess the cases of vitamin D deficiency in known population. Materials & Methods: The present study was conducted in the department of Physiology. It comprised of 480 subjects. Subjects with vitamin D level (25(OH)D) below 20 ng/ml (50 nmol/l), vitamin D insufficiency as 25(OH)D level at 21-29 ng/ml were evaluated. The serum 25(OH)D estimation was done using radioimmunoassay (RIA) method. All were supplemented with vitamin D3 60,000 IU/week for eight weeks as rapid restoration phase. Results: Out of 480 subjects, males were 68 and females were 412. The difference was significant (P- 0.02). Age group 21-30 years had 2 males and 10 females, 31-40 years had 6 males and 48 females, 41-50 years had 12 males and 88 females, 51-60 years had 20 males and 124 females and > 60 years had 28 males and 142 females. The difference was significant (P- 0.01). Mean vit D3 25(OH)D level of < 20 ng/ml was seen in 66 males and 396 females, 20-30 ng/ml was seen in 2 males and 16 females. The difference was significant (P- 0.01). Conclusion: Vitamin D is an essential vitamin required in sufficient amount for bones and teeth. Vitamin D deficiency is quite common in females.
Authors and Affiliations
Megha Kapoor, Garima Charak
Keywords
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