Evaluation of proliferation rate of osteoblast-like cells in contact with titanium alloy surfaces sandblasted to different roughness level
Journal Title: Engineering of Biomaterials / Inżynieria Biomateriałów - Year 2016, Vol 19, Issue 134
Abstract
Titanium and its alloys are very popular metallic biomaterials used for medical implants production. Despite numerous advantages of the bulk material, such implants are very often subjected to additional surface treatment in order to improve their integration within the body tissues. Besides many other available techniques, one of the most frequently used in the commercial sector is a fast and economically profitable process of abrasive blasting. It is a method in which a stream of accelerated particles collides with the implant surface what causes changes in the material properties. The following paper presents differences resulting from sandblasting of Ti-6Al-4V and Ti-6Al-7Nb specimens with blasting particles varying in size. In order to characterize the outcome of such the treatment, investigations of surface topography, chemical composition, roughness, and wettability were conducted. Finally, the behaviour of the osteoblast- -like cells adhered to the sandblasted Ti-6Al-4V and Ti-6Al-7Nb surfaces was assessed in order to evaluate potential body response towards the aforementioned materials. The results suggest a strong correlation between surface roughness, its chemistry and the type of blasting medium applied. Evaluation of the cell culture revealed a rapid decrease in cell proliferation rate onto the roughest surfaces.
Authors and Affiliations
D. Bociąga, A. Olejnik, K. Jastrzębski, J. Paradowska
Keywords
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Evaluation of proliferation rate of osteoblast-like cells in contact with titanium alloy surfaces sandblasted to different roughness level
Titanium and its alloys are very popular metallic biomaterials used for medical implants production. Despite numerous advantages of the bulk material, such implants are very often subjected to additional surface treatmen...