Evaluation of Retinal Nerve Fiber Layer Thickness using Spectral Domain-Optical Coherence Tomography in Glaucomatous, Ocular Hypertensive and Normal Eyes and its Correlation with Visual Fields

Journal Title: Journal of Clinical Research and Ophthalmology - Year 2017, Vol 4, Issue 1

Abstract

Objective: The aim of the study was to correlate the findings of peripapillary retinal nerve fiber layer (RNFL) thickness calculated with optical coherence tomography(OCT) with visual field changes in glaucomatous, ocular hypertensive and normal eyes. Materials and Methods: 30 normal, 30 ocular hypertensive and 30 glaucomatous eyes were included in the study. All underwent applanation tonometry, disc evaluation, octopus white on white (W/W) perimetry and OCT. Average and segmental RNFL thickness values were compared among all groups. A correlation was sought between global indices of perimetry and RNFL thickness in ocular hypertensive group. Results: Of the 90 eyes (mean age: 51.20±9.23 years), the mean RNFL thickness was significantly less in ocular hypertensives 83.83±26.20μm; P< 0.001) and glaucomatous eyes (55.33±34.72 μm; P <0.001), than in normal (103.27±16.23 μm). Ocular hypertensives had thinner RNFL in the superior, inferior, nasal and temporal quadrants (P < 0.001) when compared to normal. The RNFL thickness could not be significantly correlated with global indices of visual fields in ocular hypertensives. Conclusion: Optical coherence tomography is capable of detecting changes at the level of RNFL in ocular hypertensive eyes with normal appearance of discs and W/W perimetry fields.

Authors and Affiliations

Brijesh Patil, Anupama C Shetgar, Divya Teja V

Keywords

Related Articles

Bilateral Thalamic Infarction and Double Depressor Palsy Secondary to Infarction of Artery of Percheron: A case report

Introduction: Bilateral thalamic infarcts are a rare occurrence and accounts for about 22 to 35% of all the thalamic infarcts. Purpose: We report a case of bilateral thalamic infarction and double depressor palsy seconda...

Sensory Compensation in Children Following Vision Loss after Trauma and Disease

Sensory compensation or sensory substitution occurs when a sense organ, such as the eye, is lost due to trauma or disease. Individuals often experience phantom limb sensation or pain but research increasingly points towa...

Corneal Diabetes: Where to Next?

Diabetes mellitus (DM) or better known as simply diabetes is a group of metabolic diseases in which high blood sugar levels are maintained over a prolonged period. Long term complications include but not limited to heart...

Central Corneal Thickness in Nepalese Glaucoma Patients and Glaucoma Suspects

Purpose: To compare central corneal thickness (CCT) among glaucoma patients, glaucoma suspects, and normal subjects and to determine its association with glaucoma severity in Nepalese population. Methods: This study incl...

A Comparative Study of Topical Versus Peribulbar Anaesthesia in Phacoemulsification Cataract Surgery and Implantation of Intraocular Lens

Introduction: This study was conducted for evaluating and comparing levels of patient discomfort during phacoemulsification and intraocular lens implantation under topical and peribulbar anesthesia and comparative assess...

Download PDF file
  • EP ID EP231190
  • DOI 10.17352/2455-1414.000037
  • Views 105
  • Downloads 0

How To Cite

Brijesh Patil, Anupama C Shetgar, Divya Teja V (2017). Evaluation of Retinal Nerve Fiber Layer Thickness using Spectral Domain-Optical Coherence Tomography in Glaucomatous, Ocular Hypertensive and Normal Eyes and its Correlation with Visual Fields. Journal of Clinical Research and Ophthalmology, 4(1), 10-13. https://europub.co.uk/articles/-A-231190