Evaluation of Risk Factors Associated With Carcinoma Gallbladder and Outcome of Treatment in Patients Attending Tertiary Care Centre Kanpur UP.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 4
Abstract
Introduction: Gallbladder carcinoma (GBC) ranks fifth among the gastrointestinal carcinomas and is the most common cancer of the biliary tract. According to the Indian cancer registry data, incidence of GBC is 0.8%–1%.gallstones are a well-established risk factor associated with the development of GBCs in 75%–90% of cases. Surgery is indicated in only very selected cases. For the majority of patients, non operative approach to palliation is best. Gall bladder cancer for most patients is a lethal disease with a grim prognosis. Material &Method: Present study was carried out in the Department of Surgery GSVM Medical College Kanpur from January 2017 to October 2018.90 Cases with suspected gall bladder cancer were included. Results: Out of the total 90 subjects in our study, 50 patients (55.55%) were from gangetic plains77.77% patients in our study used mustard oil as the cooking medium Gall stones were present in 73 cases (81.11%) The study shows that all cases of suspected gall bladder cancer presented in later stages (stage III and IV). Discussion: The incidence of CaGB was found to be significantly high among the people living near the Ganga as compared to the subjects belonging to non-gangetic plain areas. Suspected gall bladder carcinoma cases in our study presented in later stages (stage III and IV) of the disease due to the absence of any early red flag clinical features; leading to non-operability in maximum cases. Conclusion: Primary prevention of gallbladder cancer is not expected in the near future. However, secondary prevention, primarily oriented to early diagnosis and treatment of symptomatic gallstones must be emphasized in endemic areas where cholelithiasis is highly prevalent. Prophylactic laparoscopic cholecystectomy might be cost effective. It is apparent that interventional programs are urgently needed to decrease the number of gall bladders at risk for gallbladder cancer development in high-risk areas.
Authors and Affiliations
Gulab Dhar Yadav
Keywords
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