Evaluation of Risk Factors of Cardiovascular Disease on Hypertensive PostMenopausal Women and Aged-matched Hypertensive Males

Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 4

Abstract

Background: This study compared plasma lipids and glucose levels in hypertensive post-menopausal women with age-matched hypertensive men. Methods: This is a cross sectional study that involves 100 subjects attending out-patient department of Nnamdi Azikiwe University Teaching hospital hypertensive clinics and control subjects. 25 hypertensive post-menopausal women and 25 hypertensive male subjects both within the same age range of 50-60 years. Also 25 hypertensive pre-menopausal women and 25 nonhypertensive controls both within the age range of 30-40 years. The lipid profile parameters (Total Cholesterol (TC), Triglyceride (TG), Low density Lipoprotein (LDL-C), and High Density Lipoprotein (HDL-C)) and fasting plasma glucose were determined using standard methods. The study also assessed the anthropometric indices such as BMI, SBP and DBP in each group. Results: The mean levels of TC and TG were significantly lower in post-menopausal hypertensive females when compared with the hypertensive males (p<0.05). However, the mean plasma HDL-C and LDL-C did not show any significant difference between the two groups. The comparison of the mean levels of all the parameters in hypertensive males with the non-hypertensive controls showed a significant difference (P < 0.05). The mean levels of TC and LDL-C were significantly higher in hypertensive post-menopausal women when compared with hypertensive pre-menopausal females (P<0.05). Conclusion: This study showed that menopause had altered the plasma lipids of the hypertensive post-menopausal women, but not to the extent of putting them at the same atherosclerosis scale as their male counterpart.

Authors and Affiliations

Onah, Christian Ejike

Keywords

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  • EP ID EP205673
  • DOI -
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How To Cite

Onah, Christian Ejike (2014). Evaluation of Risk Factors of Cardiovascular Disease on Hypertensive PostMenopausal Women and Aged-matched Hypertensive Males. Journal of Medical Science And clinical Research, 2(4), 638-645. https://europub.co.uk/articles/-A-205673