Evaluation of Role of Autologous Platelet Rich Fibrin in Wound Healing and Bone Regeneration after Mandibular Third Molar Surgery: A Prospective Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 5
Abstract
Background: Bony cavities filled with PRF showed healing in the half the time as compared to the time required for physiological healing. Thereby the aim of this study is to evaluate the role of autologous platelet rich fibrin in healing and bone regeneration in mandibular third molar extraction sockets. Material & Methods: All the selected patients were explained about the procedure, its related complications and the follow-up period involved in the study. The study subjects were carried out in the Department of Oral And Maxillofacial Surgery, Mahatma Gandhi College and Hospital, Jaipur with bilateral impacted mandibular 3rd molars. The subjects were evaluated for pain, swelling and pocket depth on 3rd, 7th and 30th day post-operatively. Pocket depth was measured by using William’s Graduated Probe. 10-Level Visual analog scale was used to evaluate pain. Results: Our study showed that the pain scores were measured by using VAS. There were no statistically significant differences observed between groups and swelling also statistically significant differences were observed in third days, seventh days and after one month between PRF and control side (p < 0.05). The degree of inflammation which was more on the 3rd post-PRF placement day was also significantly decreased by the after one month (P < 0.05). Conclusion: We concluded that PRF could be used for control swelling after third molar extraction surgery. Studies with a larger sample that will need a bilateral third molar removal that will be extracted in different sessions with a longer follow-up is warranted to obtain a more statistically meaningful results with respect to bone regeneration.
Authors and Affiliations
Dr Aditya Harsh
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