Evaluation of Serum 25-Hydroxyvitamin D Levels in Type 2 Diabetes Mellitus Patients
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 2
Abstract
Background: Vitamin D plays an important role in calcium metabolism and vitamin D deficiency may be associated with a range of diseases, including cardiovascular disease and type 2 diabetes and has been associated with impaired insulin action, through direct effect of vitamin D on the β-cell function. Aim: To evaluate serum 25 -Hydroxy vitamin D levels in type 2 diabetes mellitus patients. Materials And Methods: The study was conducted on 45 diagnosed type 2 Diabetes mellitus patients and 25 non-diabetic age and gender matched control in the Department of Biochemistry, Government Medical College Patiala sample was collected in plain vial and serum25-hydroxy vitamin D levels were evaluated by ELISA technique and the results were statistically analysed. Results: The Mean values of serum 25-hydroxyvitamin D levels in study group and control group were 16.31± 14.03 and 26.63 ± 16.54 respectively (Normal Value of vitamin D =30-74 ng/ml).The decrease in Vitamin D levels in study group as compared to control group shows statistically significant association(p value< 0.07) . Conclusions: Vitamin D levels appeared to be lower in diabetes mellitus type 2 patients than in the control group. These findings may have therapeutic implications as cautious vitamin D supplementation may improve glycemic control in diabetes mellitus type 2.
Authors and Affiliations
Dr. Garima Sehgal
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