Evaluation of serum biochemical profile of breast cancer patients
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 7
Abstract
Breast cancer is the most common cancer worldwide. The incidence and mortality rate is increasing in developing countries as compare to developed countries. The aim of this study was to evaluate the effect of different courses of chemotherapy treatment on serum biochemical profile of breast cancer patients. In the present study, two hundred breast cancer patients were selected to study variations in serum biochemical level of breast cancer patients. The mean values of blood urea nitrogen, creatinine, uric acid, aspartate aminotransferase (SGOT), alanine aminotransferase (SGPT) and alkaline phosphatase was found to be 32.58±19.7mg/dl, 1.05±0.59mg/dl, 8.6±1.3mg/dl, 27.3±4.02U/L, 27.9±10.24U/L and 111±2 4.04U/L before the start of chemotherapy courses. The mean values of total and direct bilirubin, total serum protein, albumin, Fasting and postprandial glucose level was 0.30±1.3mg/dl, 0.13±0.11mg/dl, 8.11±0.5g/dl, 3.5±0. 07g/dl, 96±25 mg/dl and 110±25mg/dl before the star t of chemotherapy treatment. The level of serum blood urea nitrogen, uric acid, alkaline phosphatase, bilirubin and post-prandial glucose level was found to be more than normal reference range; while the level of creatinine, aspartate aminotransferase (AST or SGOT), alanine aminotransferase (ALT or SGPT), total serum protein, albumin and fasting blood glucose level was reported to be within normal reference range during the different courses of chemotherapy. In conclusion, present results suggest serum biochemical parameters as an important diagnostic tool in the disease monitoring and metastasis.
Authors and Affiliations
Chauhan P. | Department of Genetics, M.D. University, Rohtak, Yadav R. | Department of Genetics, M.D. University, Rohtak Correspondance E mail: ritu.genetics@rediffmail.com, Kaushal V. | Department of Radiotherapy, Pt. B.D. Sharma University of Health Science, Rohtak, Beniwal P. | Department of Genetics, M.D. University, Rohtak
Keywords
Related Articles
- EP ID EP11887
- DOI -
- Views 247
- Downloads 16
LIMB SALVAGE IN RECURRENT GIANT CELL TUMOUR PROXIMAL END RADIUS
An 18years old male patient had undergone surgery for a giant cell tumour upper end of the right radius in Jan 2007. The tumour recurred within two months. Patient took alternative methods of treatment including indige...
Prevalence of general, abdominal and waist-to-hip ratio obesity among adults in the north of Iran: An ethnical comparative study
Obesity has remained as a main health problem and substantially increased during the last decade. The aim of this study is the comparison of obesity, central obesity and WHR obesity in 15-70 years old between Turkman an...
Pathology of Faculty Members’ rank Promotion in Universities and Higher Education Institutions Affiliated to the Ministry of Health and Medical Education of the Islamic Republic of Iran
The success of faculty members of medical sciences universities to promote higher ranks is through long-term evaluation of four educational, research, executive, and cultural performances them. This descriptive-analytic...
RARE PRESENTATION OF PITUITARY ADENOMA WITH OPHTHALMOPLEGIA
Pituitary Adenomas are benign intracellular tumours accounting for 10% to 15% of all intracranial neoplasms. They usually affect the adult population between the fourth and sixth decades of life. The prevalence of Pitui...
Wolves in the brain - A rare case of neuropsychiatric lupus
21 year old female with no significant past history presented with altered mental status as noted by her family members. Two days prior to presentation, she started becoming increasingly restless, tearful, loud and irri...