Evaluation of Shwasahara Effect of Karchura (Curcuma zedoaria Rosc) with special reference to Bronchodilator Action
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2019, Vol 0, Issue 0
Abstract
This ever vibrant science of life Ayurveda has bestowed us with innumerable number of herbs which have great potential in managing various types of ailments. The presently undertaken drug Karchura has been commonly used for the management of several diseases because of its significance for its various pharmacological activities. Ayurveda has given prime importance to shwasa roga as it exists both as an independent disease as well as symptom of other diseases. Shwasa may present as a troublesome disease which should be treated as early as possible. So in order to evaluate the effectiveness of Karchura in the management of shwasa an experimental study was planned. The experimental study was conducted on 24 guinea pigs which were divided into four groups. Standard histamine was used for bronchial constriction and standard antihistamine drug Chlorophenaramine was used to evaluate the Shwasahara (Bronchodilator) effect of Karchura. The efficacy of the drug was evaluated by the difference in change in pre-convulsion time before and after the drug administration. Upon comparing the results to standard antihistaminic drug, the test drug Karchura in its two different forms viz. Mula churna and Mula kashaya showed lesser percent of protection against histamine induced broncho constriction. Whereas on the other hand, Churna form of the test drug Karchura was more effective as compared to kashaya form.
Authors and Affiliations
Vijay Kappathanwar, Roshi Mahajan, Paramjeet Puri, Rekha Sharma, Shipra Sharma
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