EVALUATION OF THE ANTIBACTERIAL POTENTIAL OF DESERT TRUFFLES (Terfezia spp) EXTRACTS AGAINST METHICILLIN RESISTANT Staphylococcus aureus (MRSA)
Journal Title: Journal of Experimental Biology and Agricultural Sciences - Year 2018, Vol 6, Issue 4
Abstract
Desert truffles are well known for its medicinal and functional food values. These mushrooms are widely used for its antibacterial properties and as a source of protein in Saudi Arabia and many other countries around the world. Methicillin Resistant Staphylococcus aureus (MRSA) has been known for its virulence and multidrug resistant that became threat for hospital employees and community members. Present study was designed to test the common occurrence of MRSA isolates in hospital employees and patients by nasal swab samplings and then evaluate the antibacterial potential of desert truffles against these MRSA. PCR assays revealed that 17 (34%) bacterial isolates of nasal carriage found MRSA positive while in case of gender no significant association was reported in MRSA positive males and females. Further it was also reported that highest rate of MRSA positive isolates was found for the age group of 20-29 years, among the youngest participants. For testing antibacterial potential of Desert truffles, two wells of 6 mm diameter were punched on Muller-Hinton Agar that already had MRSA culture, one of them filled cautiously with 100μl of Terfezia claveryi extract and the other one with 100μl of Terfezia nivea, stored at 4? for 2 hours. After incubation at 37? for 24 h, the fresh crude extracts of T. claveryi showed a significant zone of inhibition (27±7.75mm) while this inhibition was reported (22.5±11.26mm) in case of T. nivea. These findings clearly indicated that extracts has remarkable antibacterial activity against MRSA. This investigation supports the traditional use of truffles for the treatment of eye infection and proved its effectiveness against MRSA which could be considered as promising antibiotic drug in near future.
Authors and Affiliations
Hanaa M. Malik, Munazza Gull, Ulfat Omar, Taha Abdullah Kumosani, Ahmed Mahmoud Al-Hejin, Hani Z Marzouki, Archana P. lyer1
Keywords
Related Articles
- EP ID EP592806
- DOI 10.18006/2018.6(4).652.660
- Views 28
- Downloads 0
Wild edible mushrooms of Nagaland, India: a potential food resource
Wild edible mushrooms (WEM) are known for its medicinal and nutritional value across the globe. WEM have become one of the most prized after food especially in the developed countries where people are mostly health consc...
Effects of integrated management of bio and chemical fertilizers on yield of maize hybrids (Zea mays L.)
Fertilizer management plays an important role in obtaining satisfactory yields from maize. In addition, fertilizer management is essential for achieving sustainable agriculture and protecting the environment. The reporte...
CRITICAL LIMITS OF SOIL AVAILABLE PHOSPHORUS FOR RAPESEED (Brassica campestris VAR. toria) IN ACIDIC SOILS OF MEGHALAYA
A pot culture experiment was conducted at School of Natural Resource Management, College of Post Graduate Studies, Central Agricultural University, Umiam, Meghalaya during Rabi season of 2016-17. The experiment was consi...
BREEDING PROBIOTIC STRAINS OF MICROORGANISMS
This research was aimed at isolating pure cultures of microorganisms that fermented lactose from the contents of the digestive tract of wild animals, and at studying their technological properties. Further, the contents...
Resistotypes of Rhodococcus equi isolated from foals with respiratory problems
Rhodococcus equi has been recognized primarily as a respiratory pathogen of equines particularly of foals between one and four months of age. R. equi is ranked among the most important disease problems in equines especia...