EVALUATION OF THE ANTIBACTERIAL POTENTIAL OF DESERT TRUFFLES (Terfezia spp) EXTRACTS AGAINST METHICILLIN RESISTANT Staphylococcus aureus (MRSA)
Journal Title: Journal of Experimental Biology and Agricultural Sciences - Year 2018, Vol 6, Issue 4
Abstract
Desert truffles are well known for its medicinal and functional food values. These mushrooms are widely used for its antibacterial properties and as a source of protein in Saudi Arabia and many other countries around the world. Methicillin Resistant Staphylococcus aureus (MRSA) has been known for its virulence and multidrug resistant that became threat for hospital employees and community members. Present study was designed to test the common occurrence of MRSA isolates in hospital employees and patients by nasal swab samplings and then evaluate the antibacterial potential of desert truffles against these MRSA. PCR assays revealed that 17 (34%) bacterial isolates of nasal carriage found MRSA positive while in case of gender no significant association was reported in MRSA positive males and females. Further it was also reported that highest rate of MRSA positive isolates was found for the age group of 20-29 years, among the youngest participants. For testing antibacterial potential of Desert truffles, two wells of 6 mm diameter were punched on Muller-Hinton Agar that already had MRSA culture, one of them filled cautiously with 100μl of Terfezia claveryi extract and the other one with 100μl of Terfezia nivea, stored at 4? for 2 hours. After incubation at 37? for 24 h, the fresh crude extracts of T. claveryi showed a significant zone of inhibition (27±7.75mm) while this inhibition was reported (22.5±11.26mm) in case of T. nivea. These findings clearly indicated that extracts has remarkable antibacterial activity against MRSA. This investigation supports the traditional use of truffles for the treatment of eye infection and proved its effectiveness against MRSA which could be considered as promising antibiotic drug in near future.
Authors and Affiliations
Hanaa M. Malik, Munazza Gull, Ulfat Omar, Taha Abdullah Kumosani, Ahmed Mahmoud Al-Hejin, Hani Z Marzouki, Archana P. lyer1
Keywords
Related Articles
- EP ID EP592806
- DOI 10.18006/2018.6(4).652.660
- Views 45
- Downloads 0
Genetic variation in maize inbred lines under temperate conditions
Present study was carried out to generate information on gene action using Hayman’s component of diallel analysis. The experimental material comprised 30 crosses which were generated by crossing between six maize inbred...
Parasitological, biochemical and clinical observations in ponies experimentally infected with Trypanosoma evansi
The present investigation aimed to study the parasitological, biochemical and clinical alterations in ponies during the course of Trypanosoma evansi experimental infection. Six female ponies were experimentally infected...
EFFECT OF INTERCROPPING ON THE DEVELOPMENT OF CASSAVA BACTERIAL BLIGHT
The effect of intercropping cassava with maize or cowpea in two arrangements i.e. both crops in the same row or in alternate rows, on cassava bacterial blight has been compared to cassava monoculture in the forest-savann...
Vegetative propagation and initial growth performance of Streblus asper Lour. – A tropical medicinal tree
Vegetative propagation of Streblus asper, an important medicinal plant, was studied for efficient rooting using different concentrations of auxins and non auxinic Boric acid. Semi hard wood cuttings of 0.9 - 1.2 cm di...
Bats: carriers of zoonotic viral and emerging infectious diseases
Bats are reported as reservoir host for several viruses, which cause significant illness in human and animals. Some of the bat transmitted zoonotic viral diseases such as Ebola, Hendra, Nipah and rabies may cause severe...