Evaluation of the Baseline Widal titre among apparently healthy individuals in Tumkuru, Karnataka, India
Journal Title: Indian Journal of Microbiology Research - Year 2016, Vol 3, Issue 4
Abstract
Background & Objectives: Enteric fever is a major public health problem in India. Widal test is a cheap, affordable and easily available and the most commonly used test for the serodiagnosis of enteric fever. The purpose of the present study is to evaluate the baseline titre for O and H antigens of Salmonella enterica subspecies enteric serotype Typhi and H antigens of Salmonella enteric subspecies enterica serotype Paratyphi A and Paratyphi B among normal healthy adult population in Tumkuru, Karnataka, India. Methods: Blood samples were collected from healthy blood donors (n= 493) who attended blood bank of this institution from January 2016-March 2016. All the samples were tested for the presence of Salmonella antibody by Widal tube agglutination test. Results: Of the 493 samples which were tested, 199(40.13%)) serum samples were positive for one or more agglutinin(≥1:20) and 294(59.63%) serum samples were negative for agglutinins(≤1:20). Out of these 340(68.96%) and 306(62.06%) samples showed a titer of >1:20 to the O and H antigen of Salmonella enterica serovar Typhi respectively. An agglutinin titre of >1:20 against H antigen of Salmonella enterica serovar Paratyphi A and Paratyphi B were found in 85(17.24%) & 119(24.13%) respectively. Conclusion: Baseline titre of 1:80 for O and H antigens of Salmonella Typhi and 1:40 for H antigens of Salmonella Paratyphi A and B were observed in the present study.
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Parimala TV
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