Evaluation of the Crimean-Congo Hemorrhagic Fever Cases Followed and Treated in Our Clinic between 2009-2013
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 15, Issue 5
Abstract
Objectives: The Crimean-Congo hemorrhagic fever virus (CCHFV) belongs to the family Bunyaviridae, genus Nairovirus, and causes severe disease in man; the reported case-fatality rate is 3%–30%. The aim of this study was to determine the epidemiological and clinical characteristics of the CCHF cases in our clinic between 2009-2013. Materials and Methods: Thirty-three patients with the diagnosis of CCHF were followed up in Kayseri Training and Research Hospital between January 2009 and September 2013. Demographic, geographic, climatic, and clinical and laboratory characteristics of all patients were investigated. All of the cases were confirmed by CCHF immunoglobulin M (IgM) and/or PCR RNA positivity. Results: According to our reports 33 CCHF cases were followed in our clinic. Of the CCHF cases, 63.6% were male. Thirty patients (90.9%) were from rural regions. Seventeen patients (51, 5%) were farmers. The median age was 46.7 years (range18-71 years). On admission, 97% of patients experienced high fever, 100% had weakness, 93.9% had headache. The disease was more usual in May, June, July. Of the CCHF cases, 69.7% had a history of tick bite. On admission, all of the patients had thrombocytopenia, 87.9% had leucopenia, 27.3% had anemia, and 87.9% had elevated AST and ALT. Oral ribavirin treatment was used in 33.3% of the CCHF cases. The case-fatality rate was 12.1% (4/33 patients). Conclusions: CCHF remains a seasonal problem in the Mid-Eastern Anatolia region of Turkey. The mortality rate in our patients was higher than reported in other studies in our country (12% vs 5%). CCHF should be accompanied with supportive care, especially including early platelet replacement.
Authors and Affiliations
İlhami Çelik, Zehra Beştepe Dursun, Filiz Kürklü Bozkır, Fatma Bahadır, Sibel Gürbüz
Clinical and Radiographical Performance of Different Types of Posts
Background: A post is an important part of restoring a tooth that has lost a coronal portion and is implicated in the type of core materials or post systems used in tooth restoration. Objectives: To evaluate and compare...
Prevalence of Glucose -6- Phosphate Dehydrogenase (G-6-PD) Deficiency in Sokoto: Liver Function and Oxidative Stress Biomarkers in Deficient Individual
Background: Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme in the pentose phosphate pathway (PPP) and plays an essential role in the oxidative stress response by producing Nicotinamide adenine dinucleotide phos...
Lower Urinary Tract Infections among Patients Diagnosed of Benign Prostate Hyperplasia in Federal Medical Centre, Bida, North Central, Nigeria
Objective: This study was aimed to identify the aetiology of bacteria associated with Benign Prostate Hyperplasia (BPH) and to determine the antimicrobial susceptibility pattern of the isolated organisms in the community...
Bloody Nipple Discharge in Infants: Case Series
Bloody nipple discharge very rarely occurs in infants and often is associated with benign mammary duct ectasia. Just because it is a rare symptom and frequently associated with adults’ mammary cancer, it is inadequately...
Corrective Osteotomy for Residual Lower Extremity Deformities Following Healed Rickets: A Retrospective Study in a Rural Hospital among Nigerian Children
Background: Rickets is the clinical manifestation of a failure of calcification of bone matrix in growing children. Although treatment of rickets is medical, residual deformities following healed/ burnt out rickets may e...