Evaluation of the Crimean-Congo Hemorrhagic Fever Cases Followed and Treated in Our Clinic between 2009-2013
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 15, Issue 5
Abstract
Objectives: The Crimean-Congo hemorrhagic fever virus (CCHFV) belongs to the family Bunyaviridae, genus Nairovirus, and causes severe disease in man; the reported case-fatality rate is 3%–30%. The aim of this study was to determine the epidemiological and clinical characteristics of the CCHF cases in our clinic between 2009-2013. Materials and Methods: Thirty-three patients with the diagnosis of CCHF were followed up in Kayseri Training and Research Hospital between January 2009 and September 2013. Demographic, geographic, climatic, and clinical and laboratory characteristics of all patients were investigated. All of the cases were confirmed by CCHF immunoglobulin M (IgM) and/or PCR RNA positivity. Results: According to our reports 33 CCHF cases were followed in our clinic. Of the CCHF cases, 63.6% were male. Thirty patients (90.9%) were from rural regions. Seventeen patients (51, 5%) were farmers. The median age was 46.7 years (range18-71 years). On admission, 97% of patients experienced high fever, 100% had weakness, 93.9% had headache. The disease was more usual in May, June, July. Of the CCHF cases, 69.7% had a history of tick bite. On admission, all of the patients had thrombocytopenia, 87.9% had leucopenia, 27.3% had anemia, and 87.9% had elevated AST and ALT. Oral ribavirin treatment was used in 33.3% of the CCHF cases. The case-fatality rate was 12.1% (4/33 patients). Conclusions: CCHF remains a seasonal problem in the Mid-Eastern Anatolia region of Turkey. The mortality rate in our patients was higher than reported in other studies in our country (12% vs 5%). CCHF should be accompanied with supportive care, especially including early platelet replacement.
Authors and Affiliations
İlhami Çelik, Zehra Beştepe Dursun, Filiz Kürklü Bozkır, Fatma Bahadır, Sibel Gürbüz
Keywords
Related Articles
- EP ID EP341176
- DOI 10.9734/BJMMR/2016/25724
- Views 73
- Downloads 0
The Clinical, Diagnostic, and Therapeutic Characteristics of 22 Male Patients with Breast Cancer
Aim: The aim of this study is to evaluate the clinicopathological, diagnostic, and therapeutic features of male breast cancer. Study Design: This is a retrospective clinical study. Methodology: Twenty-two male patients...
Histological and Immunohistochemical Study on Nitric Oxide Synthase and Effects of Angiotensin Receptor Blockade in Early Phase of Diabetes in Rat Kidney
Hypothesis: Several studies demonstrated that the patho-physiologic and morphologic changes in early diabetic nephropathy were mediated by either an increase or decrease in the nitric oxide (NO) production and/or activit...
A Review of Helicobacter pylori Infection in Patients with Diabetes Mellitus
Gastrointestinal symptoms, such as abdominal discomfort, chronic abdominal pain, dysphagia, heartburn, nausea, vomiting, diarrhea and constipation are more common in patients with Diabetes Mellitus (DM) than in the gener...
Impacts of Beautiful Natural Surroundings on Happiness: Issues of Environmental Disruption, Food, Water Security and Lifestyle in Modern Times
Purpose: Recently, purpose in life (PIL) drawn from existentialism and the concept of ikigai [meaning in his/her life] from Japanese classical literature have been recognized as effective ways to manage stress. PIL/ikiga...
Evaluation of Maternal Thyroid Hormone Status and Atherogenic Potency in Pre Eclampsia in Kolar District- A South West of India
Aim: To determine maternal thyroid hormone status and lipid profile in preeclampsia. Study Design: A prospective case control study consist of two groups such as group 1 normotensive non-preeclamptic group and group 2 a...