EVALUATION OF THE EFFECTS OF MODERATE TO SEVERE SMOKING ON RETINAL NERVE FIBRE LAYER THICKNESS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 6
Abstract
BACKGROUND Smoking causes serious health problems worldwide. This study was intended to evaluate the possible structural changes like thickness in the retinal nerve fibre layer (RNFL) of moderate to heavy smokers and compare them with those of healthy nonsmokers using time domain optical coherence tomography (TD-OCT). MATERIALS AND METHODS We included 100 active smokers (35 cases are heavy smokers and 65 cases are moderate smokers) and 100 age- and sexmatched healthy non-smokers between 20 years to 50 years for this cross-sectional study. After a full ophthalmological examination, TD-OCT was done for all participants and peripapillary RNFL thickness was measured in all four quadrants in both the groups and then compared. RESULTS Mean age of smokers was 38.65±8.18. Mean ages of severe smokers (SS), moderate smokers (MS) and non-smokers (NS) were 43.2±7.09 years, 39.85±7.59 years and 36.11±8.06 years respectively. Age matched analysis of RNFL thickness showed significant difference between smokers and non-smokers. It showed significant decrease in average thickness specially over inferior (129.82±19.9), superior (123.48±20.48) and nasal quadrants (82.57±21.69) (p values <0.001). Severe smokers have significant RNFL thinning over nasal quadrant (p <0.001) than moderate smokers. However, temporal quadrant showed no difference in both the cases and controls. CONCLUSION Smoking causes significant RNFL thinning in chronic, healthy cigarette smokers. OCT could be a useful tool for early detection of ocular damage in chronic healthy smokers. However, no significant correlation was found between number of cigarettes smoked per day and RNFL thinning.
Authors and Affiliations
Sheuli Kumar, Swati Majumda, Suman Mukherjee, Mukul C. Biswas, Pinaki Sengupta
Keywords
Related Articles
- EP ID EP610165
- DOI 10.18410/jebmh/2019/79
- Views 73
- Downloads 0
ROLE OF CT IN DIFFERENTIATION OF MUCINOUS AND NON-MUCINOUS CARCINOMAS OF THE RECTUM
BACKGROUND Colorectal carcinomas can broadly be classified as either non-mucinous or mucinous. Usually, mucinous adenocarcinomas present at a more advanced stage, have more aggressive local spread and have an increased i...
PROPHYLACTIC USE OF EPHEDRINE TO ATTENUATE THE HAEMODYNAMIC RESPONSES TO PROPOFOL
BACKGROUND The beginning of anaesthesia since October 16th 1846. THE ETHER DAY Inhalational methods had dominated the practice of Anaesthesia. The most important factor in the increasing popularity of intravenous anaesth...
A COMPARATIVE STUDY BETWEEN CONVENTIONAL AND COLLAGEN DRESSING IN THE HEALING OF FOOT ULCERS
BACKGROUND Foot ulcer is a major disease-causing disability to many patients around the world. Treatment of foot ulcer remains a major healthcare issue; and especially diabetic foot ulcer accounts for 15% of incidence wh...
DOPPLER ASSESSMENT IN PREGNANCY-INDUCED HYPERTENSION AND USEFULNESS OF DOPPLER IN PREDICTING FOETAL OUTCOME
BACKGROUND Normal foetal growth and development depends on adequate perfusion of the intervillous space through the maternal spiral arterioles. Reduced perfusion is associated with asymmetrical retardation of the foetal...
INDUCTION THERAPY IN RENAL TRANSPLANTATION WITH ANTITHYMOCYTE GLOBULIN AND BASILIXIMAB- A SINGLE CENTRE RETROSPECTIVE STUDY
BACKGROUND Renal transplantation is the best available form of renal replacement therapy. Induction therapy pre-transplant reduces the incidence of graft rejections. We present a retrospective study comparing different i...