Evaluation of the Effects of Petrochemical to Liver Enzymes of Fuel Attendants in Oluyole Area, Ibadan, Nigeria
Journal Title: Journal of Clinical Medical Research - Year 2024, Vol 5, Issue 3
Abstract
Probability of adverse health to individuals along the distribution chain, especially fuel attendants. Petrochemical industries, including fuel stations, provide an exposure scenario that increases the vulnerability of front-line staff to gasoline-related ill-health as there are typically more than 150 chemicals in petrol, including small amounts of benzene, toluene, xylene, ethyl benzene, hydrocarbons, cyanides, phenols, heavy metals, toluene and trace amounts of some contaminants, such as lead which are detrimental to the health of an individual. About 5mls of venous blood Samples were collected from 200 persons in Oluyole area, Ibadan. They were each given a questionnaire and an informed consent form to complete. Since 100 of them worked as fuel attendants at different filling stations, they were included in the case group. Among other things, their primary direct exposure sources were inhalation and skin contact. Since they don’t trade gasoline or work in the oil sector, the other 100 people were the control group. The requirements for inclusion included not having a history of chronic illnesses, such as hepatitis, diabetes, renal failure or blood problems, as well as not using any particular medications, smoking or drinking alcohol. The following parameters were measured after the samples were spun and separated: total protein, plasma albumin, globulin, aspartate Aminotransferase (AST), Aslanine Aminotransferase (ALT) and Alkaline Phospahatase (ALP). The blood was drawn for the laboratory tests in the morning. P<0.01 was seen for high ALT, AST and ALP, which were 86.3%, 111.4% and 88.5%, respectively. Additionally, there was a 37.2%, 37.8% and 36.4% (P<0.01) drop in Total Protein, Albumin and Globulin levels relative to the controls. This study demonstrated that subjects exposed to petrochemicals may experience liver alterations. However, petrochemicals including benzene and other compounds such as acetylaldehyde, formaldehyde which are components in the petrochemicals can lead to numerous toxic health effects associated with functional aberration of vital organs in the body such as the liver with a significant increase in the ALT, AST, ALP and a decrease in Total protein, Albumin and Globulin.
Authors and Affiliations
Usiobeigbe OS1, Obohwemu KO2, Omolumen LE1, Idehen IC3, Udoaka A4, Akindele IA5, Asibor E6, Oriaifo BA7, Ikyaagba RO8, Omoviye OE9, Echekwube ME6, Lagundoye SB10, Bello GO11, Kehinde A12, Aliche PC13, Edo EO14, Fawole MF15
Keywords
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- EP ID EP751729
- DOI https://doi.org/10.46889/JCMR.2024.5314
- Views 56
- Downloads 0
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