EVALUATION OF THE HYPOGLYCEMIC AND ANTI-HYPERGLYCEMIC ACTIVITIES OF AQUEOUS AND HYDROETHANOLIC EXTRACTS OF ERYTHROCOCCA ANOMALA LEAVES IN RAT.
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 4
Abstract
Erythrococca anomala (Euphorbiaceae) is an annual medicinal plant, widely used in traditional medicine in Cote d’Ivoire and sub-Saharan Africa as an anti-inflammatory, laxative and purgative. In the present work, the aim was to evaluate the hypoglycemic and anti-hyperglycemic activity of the aqueous and hydroethanolic extracts of the leaves of this plant in the rat. The blood glucose was determined using a glucose reader Test strips). Administered orally at doses of 100 and 200 mg / kg body weight the extracts induce dose-dependent hypoglycemia in the rat. These aqueous and hydroethanolic extracts at a dose of 200 mg / kg body weight significantly reduced the hyperglycemia caused by administration by glibenclamide, the reference anti-hyperglycemic molecule (10 mg / kg body weight). Oral glucose at a dose of 5 mg / kg body weight to the rat.
Authors and Affiliations
Miezan Bile Aka Patrice
Keywords
Related Articles
- EP ID EP628976
- DOI -
- Views 181
- Downloads 0
RELEVANCE OF SERUM LH/FSH/PROLACTIN AND ANTI MULLERIAN HORMONE ESTIMATION IN INVITRO FERTILIZATION
Background: Infertility has been considered a field of importance in public health circles due to its high prevalence and its social effects on affected couples and families. Detection and evaluation of incidence of infe...
EVALUATION OF DAILY CHANGES OF GLOMERULAR FILTRATION RATES IN PATIENTS RECEIVING COLISTIN DUE TO ACINETOBACTER INFECTION IN INTENSIVE CARE UNITE
Aim: To examine relationship between the frequency of secondary nephrotoxicity, mortality rates and daily glomerular filtration rate [GFR] in patients receiving colistin due to acinetobacter infection in Intensive Care U...
Ara-C SYDROME FOLLOWING LOW DOSE CYTARABINE INFUSION IN A CHILD TREATED FOR ACUTE MYELOID LEUKEMIA (AML)
Cytarabine (Ara-C) syndrome is a rare condition characterized by acute febrile reaction, myalgia, bone pain and occasionally chest pain, maculopapular rash, conjuctivitis and malaise. This complication is mostly describe...
BLOOD MORPHOLOGY IN PATIENTS SUFFERING FROM ENTERIC FEVER.
OBJECTIVE: To study peripheral blood morphology in patients suffering from enteric fever in Pathology Deptt, Khalifa Gul Nawaz Teaching Hospital Bannu. Khyber Pakhtun Khwa. Pakistan. This was one year study from January...
PHYTOCHIMICAL TESTS AND LARVICIDE ACTIVITY OF THREE ORGANIC EXTRACTS FROM THE SEEDS OF INDIGOFERA PILOSA ON LARVAE OF MOSQUITOS
In the search for alternative method beside the use of dangerous insecticides for health and the environment, the vegetable kingdom offers many possibilities. Work is carried out in this direction and showed an effective...