EVALUATION OF THE HYPOGLYCEMIC AND ANTI-HYPERGLYCEMIC ACTIVITIES OF AQUEOUS AND HYDROETHANOLIC EXTRACTS OF ERYTHROCOCCA ANOMALA LEAVES IN RAT.
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 4
Abstract
Erythrococca anomala (Euphorbiaceae) is an annual medicinal plant, widely used in traditional medicine in Cote d’Ivoire and sub-Saharan Africa as an anti-inflammatory, laxative and purgative. In the present work, the aim was to evaluate the hypoglycemic and anti-hyperglycemic activity of the aqueous and hydroethanolic extracts of the leaves of this plant in the rat. The blood glucose was determined using a glucose reader Test strips). Administered orally at doses of 100 and 200 mg / kg body weight the extracts induce dose-dependent hypoglycemia in the rat. These aqueous and hydroethanolic extracts at a dose of 200 mg / kg body weight significantly reduced the hyperglycemia caused by administration by glibenclamide, the reference anti-hyperglycemic molecule (10 mg / kg body weight). Oral glucose at a dose of 5 mg / kg body weight to the rat.
Authors and Affiliations
Miezan Bile Aka Patrice
Keywords
Related Articles
- EP ID EP628976
- DOI -
- Views 163
- Downloads 0
EFFECT OF ALLIUM SATIVUM ESSENTIAL OIL ON THE GLYCEMIC CONTROL AND HYPERLIPIDEMIA IN TYPE 2 DIABETES MELLITUS SUBJECTS
Background: Allium sativum (AS) is used as herbal medicine since time immemorial. Allium sativum has shown anti- hyperglycemic, anti oxidant, anti cancer, and anti atherogenic activity. Objective: To analyze the glycemic...
REJECT-REPEAT ANALYSIS OF PLAIN RADIOGRAPHS AS A QUALITY INDICATOR AT UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL (UMTH)
Objective: To determine the level of improvement of reject rate, persistent main cause of repeated films and re-occurring most common projection(s). Methodology: A prospective design was carried out on radiographs of poo...
OXIDATIVE STRESS AND SOME INFLAMMATORY BIOMARKERS IN PATIENTS WITH CORONARY HEART DISEASE
Myeloperoxidase is a marker of oxidative stress and is released after neutrophils Energizing.It has potent pro-oxidative and proinflammatory properties. This study was objectives toinvestigate theimpactof myeloperoxidasea...
UTILITY OF IMMUNOHISTOCHEMICAL MARKERS IN THE DIAGNOSIS OF COMMON SOFT TISSUE SARCOMAS IN ADULTS: A BRIEF REVIEW
Soft tissue sarcomas are a complex group of neoplasms arising from mesenchymal tissues. They present great difficulties for the practicing surgical pathologist due to their variety and several lines of differentiation. T...
TRAUMATIC BASAL GANGLIA BLEED
Traumatic Basal ganglia bleed is not a frequent hemorrhagic lesion of basal ganglia or adjacent structures. The lesion determines clinical signs related to particular sub cortical structures involved, with incidence of 3...