Evaluation of the Most Common Complications of Sickle Cell Anemia and Management in Children: Simple Literature Review
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 72, Issue 2
Abstract
<span>Background: </span><span>Sickle cell anemia is an autosomal structural defect that affect the hemoglobin. It is associated with reduction in the RBC life span especially under stress. As a result of this structural defect the RBCs takes a sickle shape which is associated with a lot of complications that significantly have an effect on the </span><span>patient’s life. </span><span>Objective: </span><span>In this study, we aim at evaluating the most common complication of sickle cell anemia. Also, the assessment of the various management plans to prevent it if occurred. </span><span>Methods: </span><span>PubMed database were used for articles selection as well as all relevant articles to our research interest with the following topics: Sickle cell anemia, Complications, Mortality, Prevention and Management. We excluded other articles, which are not related to this field. The data were extracted according to specific form in which it is going to be reviewed by the group members. </span><span>Conclusion: </span><span>Sickle cell anemia have various complications that have impact on quality of life and arise from effect of three main pathophysiological mechanisms i.e. Vasooclussive, hyper-haemolytic and infective complications. Hydroxyurea, chronic blood transfusion, and routine Transcranial Doppler Ultrasound are still the most useful preventive measures of SCA complications. </span>
Authors and Affiliations
Eman Helal
Keywords
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- EP ID EP584066
- DOI 10.21608/ejhm.2018.9076
- Views 111
- Downloads 0
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