Evaluation of the Relationship Between Body Mass Index and Vitamin D in Women Admitted to the Obesity School
Journal Title: Scholars Academic Journal of Biosciences - Year 2015, Vol 3, Issue 9
Abstract
Abstract: Although the vitamin D is classically known for its role in bone metabolism, it plays an extensive role for overall body beyond the musculoskeletal system. In this study, we aimed to evaluate vitamin D status in obese women and to investigate the relationship between vitamin D and severity of obesity which classifed according to body mass index (BMI). The study involved 259 women. The study population were divided into two groups as obesity and non-obesity group according to their BMI values (kg/m2). The obesity group consisted of 127 women and non-obesity group consisted of 132 women. Subjects in obesity group were selected from women who admitted to “The Obesity School Program”. Serum 25-hydroxyvitamin D [25(OH)D], intact parathormon (iPTH), insulin, calcium, phosphorus, and glucose concentrations were measured and HOMA IR values were calculated. Mean values for all variables were compared between obese and non-obese group using t test. The relationship between measured parameters was evaluated by Pearson’s correlation coefficient. For all statistical tests, P < 0.05 was considered statistically significant. Serum iPTH and HOMA IR values were higher in obese group, and serum 25(OH)D values were lower in obese group. Vitamin D deficiency was higher in obese group. Negative correlation was found between serum 25(OH)D levels, age, and BMI. According to our results, we observed a negative correlation between BMI and 25(OH)D. These results should be supported by further experimental studies. Keywords: 25-hydroxyvitamin D, body mass index, insulin resistance, obesity, parathyroid hormone.
Authors and Affiliations
Fatma Emel Kocak, Turkan Pasali Kilit, Yasemin Korkut, Inci Arikan, Mustafa Yontem, Sevgi Nur Alakus
Keywords
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